Analysis of Autophagy for Liver Pathogenesis

Nazmul Huda, Hui Zou, Shengmin Yan, Bilon Khambu, Xiao-Ming Yin

Research output: Contribution to journalArticle

Abstract

The autophagy pathway in hepatocytes is well characterized. Autophagy plays a critical role in the normal function of the liver. A growing number of studies suggest that there is a mechanistic relationship between autophagy and the pathogenesis of human diseases including liver diseases. Here we focus on the methods assessing the level of lipids, lipid peroxidation, and lipophagy in the liver, which would be particularly relevant to the study of fatty liver diseases.

Original languageEnglish (US)
Pages (from-to)481-489
Number of pages9
JournalMethods in molecular biology (Clifton, N.J.)
Volume1880
DOIs
StatePublished - Jan 1 2019

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Keywords

  • Autophagy
  • Fatty liver diseases
  • Hepatocytes
  • Immunofluorescence
  • Lipid droplets
  • Lipophagy
  • Reactive oxygen species

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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