Analysis of the vascular potential of hematopoietic stem cells.

Steven M. Guthrie, Sergio Caballero, Robert N. Mames, Maria B. Grant, Edward W. Scott

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The hematopoietic stem cells residing in the bone marrow have tremendous proliferative and self-renewing capacity, and until recently these cells were thought to produce only progeny of the blood lineages. We have recently demonstrated that these cells are capable of producing endothelial cells of blood vessels. This chapter will outline the methodology for producing chimeric mice through labeled bone marrow transplantation and induction of these donor cells in order to track their plasticity, or their ability to produce non-hematopoietic tissues, specifically blood vessels.

Original languageEnglish (US)
Pages (from-to)369-380
Number of pages12
JournalMethods in molecular medicine
Volume105
StatePublished - 2005
Externally publishedYes

Fingerprint

Hematopoietic Stem Cells
Blood Vessels
Bone Marrow Transplantation
Endothelial Cells
Bone Marrow

Cite this

Guthrie, S. M., Caballero, S., Mames, R. N., Grant, M. B., & Scott, E. W. (2005). Analysis of the vascular potential of hematopoietic stem cells. Methods in molecular medicine, 105, 369-380.

Analysis of the vascular potential of hematopoietic stem cells. / Guthrie, Steven M.; Caballero, Sergio; Mames, Robert N.; Grant, Maria B.; Scott, Edward W.

In: Methods in molecular medicine, Vol. 105, 2005, p. 369-380.

Research output: Contribution to journalArticle

Guthrie, SM, Caballero, S, Mames, RN, Grant, MB & Scott, EW 2005, 'Analysis of the vascular potential of hematopoietic stem cells.', Methods in molecular medicine, vol. 105, pp. 369-380.
Guthrie SM, Caballero S, Mames RN, Grant MB, Scott EW. Analysis of the vascular potential of hematopoietic stem cells. Methods in molecular medicine. 2005;105:369-380.
Guthrie, Steven M. ; Caballero, Sergio ; Mames, Robert N. ; Grant, Maria B. ; Scott, Edward W. / Analysis of the vascular potential of hematopoietic stem cells. In: Methods in molecular medicine. 2005 ; Vol. 105. pp. 369-380.
@article{5c9d3c5f61b7418fa554d0da07d14987,
title = "Analysis of the vascular potential of hematopoietic stem cells.",
abstract = "The hematopoietic stem cells residing in the bone marrow have tremendous proliferative and self-renewing capacity, and until recently these cells were thought to produce only progeny of the blood lineages. We have recently demonstrated that these cells are capable of producing endothelial cells of blood vessels. This chapter will outline the methodology for producing chimeric mice through labeled bone marrow transplantation and induction of these donor cells in order to track their plasticity, or their ability to produce non-hematopoietic tissues, specifically blood vessels.",
author = "Guthrie, {Steven M.} and Sergio Caballero and Mames, {Robert N.} and Grant, {Maria B.} and Scott, {Edward W.}",
year = "2005",
language = "English (US)",
volume = "105",
pages = "369--380",
journal = "Methods in molecular medicine",
issn = "1543-1894",
publisher = "Humana Press",

}

TY - JOUR

T1 - Analysis of the vascular potential of hematopoietic stem cells.

AU - Guthrie, Steven M.

AU - Caballero, Sergio

AU - Mames, Robert N.

AU - Grant, Maria B.

AU - Scott, Edward W.

PY - 2005

Y1 - 2005

N2 - The hematopoietic stem cells residing in the bone marrow have tremendous proliferative and self-renewing capacity, and until recently these cells were thought to produce only progeny of the blood lineages. We have recently demonstrated that these cells are capable of producing endothelial cells of blood vessels. This chapter will outline the methodology for producing chimeric mice through labeled bone marrow transplantation and induction of these donor cells in order to track their plasticity, or their ability to produce non-hematopoietic tissues, specifically blood vessels.

AB - The hematopoietic stem cells residing in the bone marrow have tremendous proliferative and self-renewing capacity, and until recently these cells were thought to produce only progeny of the blood lineages. We have recently demonstrated that these cells are capable of producing endothelial cells of blood vessels. This chapter will outline the methodology for producing chimeric mice through labeled bone marrow transplantation and induction of these donor cells in order to track their plasticity, or their ability to produce non-hematopoietic tissues, specifically blood vessels.

UR - http://www.scopus.com/inward/record.url?scp=16644397786&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=16644397786&partnerID=8YFLogxK

M3 - Article

C2 - 15492408

AN - SCOPUS:16644397786

VL - 105

SP - 369

EP - 380

JO - Methods in molecular medicine

JF - Methods in molecular medicine

SN - 1543-1894

ER -