Anatomic study of the lamina terminalis: Neurosurgical relevance in approaching lesions within and around the third ventricle

R. Shane Tubbs, Ha Son Nguyen, Marios Loukas, Aaron A. Cohen-Gadol

Research output: Contribution to journalArticle

2 Scopus citations


Background The lamina terminalis (LT) represents an important neurosurgical corridor by which to fenestrate the third ventricle into the subarachnoid space or to approach lesions of the third ventricle. However, a comprehensive review of its anatomy and approaches to it for various pathologies is lacking in the literature. We studied the anatomy of the LT in 21 cadavers and described the LT as observed in cadaveric dissections. We also reviewed the literature regarding the detailed anatomy and pathology of the LT. In addition, a case illustration that demonstrates the use of this structure as a corridor to third ventricular tumors is presented. Our aim was to explore the anatomy of the LT through cadaveric dissection, a review of the literature, and a case study. Methods Twenty-one adult cadaver heads underwent microdissection of the LT with a focus on the working distance available to enter the third ventricle and related vascular structures. Results Inferior to the anterior communicating artery was the safer region to open due to the lack of perforating arteries. A working distance of approximately 1 cm can be expected through the LT. Conclusions This information may aid neurosurgeons during approaches through and around the LT.

Original languageEnglish (US)
Pages (from-to)1149-1156
Number of pages8
JournalChild's Nervous System
Issue number8
StatePublished - Aug 1 2012



  • Anatomy
  • Brain
  • Lamina terminalis
  • Neurosurgery
  • Surgical technique
  • Third ventricle

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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