Angiomyolipoma of kidney with lymph node involvement. DNA flow cytometric analysis

J. Y. Ro, A. G. Ayala, A. El-Naggar, D. J. Grignon, S. F. Hogan, D. R. Howard

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

We performed DNA flow-cytometric analysis in three cases of angiomyolipoma of the kidney with lymph node involvement. The primary tumors of the kidneys and tumors in the lymph nodes of all patients contained diploid DNA. All three patients have been monitored for longer than 1 year and have no evidence of recurrence or metastasis. The lack of aneuploidy in both the kidney and the lymph nodes in our patients, although not excluding malignant neoplasia, supports the benign and multifocal nature of this lesion. Larger studies with long-term follow-up are reported to confirm this conclusion.

Original languageEnglish (US)
Pages (from-to)65-67
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume114
Issue number1
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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