Annexin 6 immunoreactivity in select cell populations in the rat brain

Research output: Contribution to journalArticle

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Abstract

We examined the distribution of annexin 6 (ANX6) in rat brain with immunohistochemistry (IHC). Several neuronal cell populations were intensely labeled with the ANX6 monoclonal antibody (MAb), including layer 5 of neocortex, the lateral septum, the lateral hypothalamic area, the red nucleus, and the Purkinje cell layer in cerebellum. Neuronal immunolabeling was localized to the nucleus and the cytosol. Darkly stained ANX6-immunoreactive glia, with the morphology characteristic of astrocytes, were abundant in the hippocampus, substantia nigra reticulata, and cerebellum. Evidence suggests that ANX6 may function in neuronal and glial calcium-dependent processes.

Original languageEnglish (US)
Pages (from-to)1277-1280
Number of pages4
JournalJournal of Histochemistry and Cytochemistry
Volume50
Issue number9
DOIs
StatePublished - Sep 2002

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Annexins
Brain
Neuroglia
Cerebellum
Population
Lateral Hypothalamic Area
Red Nucleus
Purkinje Cells
Neocortex
Astrocytes
Cytosol
Hippocampus
Immunohistochemistry
Monoclonal Antibodies
Calcium

Keywords

  • Basal forebrain
  • Calcium-binding protein
  • Cerebral cortex
  • Lateral hypothalamus
  • Radial glia

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology

Cite this

Annexin 6 immunoreactivity in select cell populations in the rat brain. / Moga, Margaret M.; Zhou, Dan.

In: Journal of Histochemistry and Cytochemistry, Vol. 50, No. 9, 09.2002, p. 1277-1280.

Research output: Contribution to journalArticle

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