Antecedents of adherence to antituberculosis therapy

Marcia McDonnell, Joan Turner, Michael T. Weaver

Research output: Contribution to journalArticle

25 Scopus citations


This correlational study identified antecedents of adherence to antituberculosis (anti-TB) therapy in a convenience sample of 62 English-speaking adults. From a demographic perspective, the study sample was similar to the referent population of TB patients in Georgia. A variety of parametric analyses revealed the following: The mean self-reported adherence score was 92.6% (SD = 3.3). Higher levels of self-reported adherence were associated with an annual income of $11,000 or more, education beyond high school, no current alcohol use, perceived support and absence of barriers to medication taking, strong intentions to adhere, and a high capacity for self-care. Those six variables accounted for 28% of adherence variance, F(6, 44) of 4.3, p = 0.0017. Additionally, belief in the usefulness and benefit of the medications was strongly correlated with intentions to adhere (r = 0.83, p < 0.001), and interpersonal aspects of care was significantly correlated with perceptions of medication utility (r = 0.65, p < 0.001), supports/barriers (r = 0.44, p < 0.001), intentions (r = 0.69, p < 0.001), and self-care (r = -0.42, p < 0.01). Persons who were diagnosed with both TB and human immunodeficiency virus (HIV) reported significantly lower adherence.

Original languageEnglish (US)
Pages (from-to)392-400
Number of pages9
JournalPublic Health Nursing
Issue number6
StatePublished - Nov 1 2001


  • Adherence
  • Self-care agency
  • Tuberculosis

ASJC Scopus subject areas

  • Nursing(all)
  • Public Health, Environmental and Occupational Health

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