Anti-Phospholipid Antibodies in Cerebrospinal Fluid But Not Serum From a Boy With Psychosis

Deborah K. Sokol, Lan S. Chen, Dawn R. Wagenknecht, John A. McIntyre

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A 12-year-old African American boy with mental retardation and Asperger's disorder presented with acute psychosis. Antiphospholipid antibody testing with enzyme-linked immunosorbent assay showed increased levels of immunoglobulin G anticardiolipin antibodies in the cerebrospinal fluid, but not in the serum. Although antiphospholipid antibodies have been reported in the serum of patients with thrombotic and neurologic disorders, there are only a few reports of these antibodies in cerebrospinal fluid. This finding is consistent with a recent report of antiphospholipid antibodies found in the cerebrospinal fluid of adults with acute psychosis.

Original languageEnglish (US)
Pages (from-to)293-294
Number of pages2
JournalPediatric neurology
Issue number4
StatePublished - Oct 1 2008

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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