Antidepressant xerogenic medications and restoration rates

D. Brad Rindal, William A. Rush, Dawn Peters, Gerardo Maupome

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objectives: This report examines the association between xerogenic antidepressant medication use and dental restorations (a proxy for dental caries). Methods: Data for this study was collected from the electronic databases of two large dental group practices associated with two managed care organizations. The population examined was at least 55-year-old on the reference date and had at least 48 months of concurrent dental, medical and pharmacy coverage. We identified 915 individuals whose only exposure to a xerogenic medication was to an antidepressant. This group was compared with a group not on any medications and to a group on medications without any known xerostomic side effect. Results: Poisson regression was used to compare restoration occurrence and restoration rates among the three groups. The antidepressant medication and the no xerogenic medication groups were more likely to have restorations than the no medication group but there was no difference in restoration rates between the two medication groups. The mean restoration rates were significantly different between the three groups with the antidepressant group having the highest restoration rate. The no xerogenic group also had a higher rate than the no medication group but not as high as the antidepressant group rate. Conclusions: This study provides objective quantification of the long-term effects that anti-depressant medications have on restoration use.

Original languageEnglish (US)
Pages (from-to)74-80
Number of pages7
JournalCommunity Dentistry and Oral Epidemiology
Volume33
Issue number1
DOIs
StatePublished - Feb 2005
Externally publishedYes

Fingerprint

Antidepressive Agents
Dental Group Practices
Tooth
Dental Caries
Managed Care Programs
Proxy
Organizations
Databases
Population

Keywords

  • Antidepressants
  • Caries
  • Depression
  • Rates
  • Restorations
  • Xerostomia

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Antidepressant xerogenic medications and restoration rates. / Brad Rindal, D.; Rush, William A.; Peters, Dawn; Maupome, Gerardo.

In: Community Dentistry and Oral Epidemiology, Vol. 33, No. 1, 02.2005, p. 74-80.

Research output: Contribution to journalArticle

Brad Rindal, D. ; Rush, William A. ; Peters, Dawn ; Maupome, Gerardo. / Antidepressant xerogenic medications and restoration rates. In: Community Dentistry and Oral Epidemiology. 2005 ; Vol. 33, No. 1. pp. 74-80.
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