Antineuronal (anti-Ri) antibodies in a patient with steroid-responsive opsoclonus-myoclonus

E. J. Dropcho, L. B. Kline, J. Riser

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Abstract

A 45-year-old woman developed opsoclonus, myoclonus, and severe truncal and gait ataxia. Serum and CSF contained IgG antibodies that appear to be identical to 'anti-Ri' antibodies associated with paraneoplastic opsoclonus and ataxia. The patient had a fluctuating course with exacerbations that responded well to corticosteroids and later to cyclophosphamide. Her anti-Ri antibody titer has declined significantly but still remains high. After more than 3 years of follow-up, no neoplasm has been detected.

Original languageEnglish (US)
Pages (from-to)207-211
Number of pages5
JournalNeurology
Volume43
Issue number1
StatePublished - Jan 1 1993

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ASJC Scopus subject areas

  • Clinical Neurology

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