Antineuronal (anti-Ri) antibodies in a patient with steroid-responsive opsoclonus-myoclonus

Edward Dropcho, L. B. Kline, J. Riser

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

A 45-year-old woman developed opsoclonus, myoclonus, and severe truncal and gait ataxia. Serum and CSF contained IgG antibodies that appear to be identical to 'anti-Ri' antibodies associated with paraneoplastic opsoclonus and ataxia. The patient had a fluctuating course with exacerbations that responded well to corticosteroids and later to cyclophosphamide. Her anti-Ri antibody titer has declined significantly but still remains high. After more than 3 years of follow-up, no neoplasm has been detected.

Original languageEnglish (US)
Pages (from-to)207-211
Number of pages5
JournalNeurology
Volume43
Issue number1
StatePublished - 1993
Externally publishedYes

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Opsoclonus-Myoclonus Syndrome
Ataxia
Anti-Idiotypic Antibodies
Gait Ataxia
Steroids
Ocular Motility Disorders
Cyclophosphamide
Adrenal Cortex Hormones
Immunoglobulin G
Antibodies
Serum
Neoplasms

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Antineuronal (anti-Ri) antibodies in a patient with steroid-responsive opsoclonus-myoclonus. / Dropcho, Edward; Kline, L. B.; Riser, J.

In: Neurology, Vol. 43, No. 1, 1993, p. 207-211.

Research output: Contribution to journalArticle

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