Antipsychotics in the treatment of autism

David J. Posey, Kimberly A. Stigler, Craig A. Erickson, Christopher J. McDougle

Research output: Contribution to journalReview article

91 Scopus citations

Abstract

Atypical antipsychotics have become indispensable in the treatment of a variety of symptoms in autism. They are frequently used to treat irritability and associated behaviors including aggression and self injury. They may also be efficacious for hyperactivity and stereotyped behavior. This review presents the rationale for the use of this drug class in autism and reviews the most important studies published on this topic to date. Significant adverse effects, including weight gain and the possibility of tardive dyskinesia, are reviewed. Future research directions are discussed.

Original languageEnglish (US)
Pages (from-to)6-14
Number of pages9
JournalJournal of Clinical Investigation
Volume118
Issue number1
DOIs
StatePublished - Jan 2 2008

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Posey, D. J., Stigler, K. A., Erickson, C. A., & McDougle, C. J. (2008). Antipsychotics in the treatment of autism. Journal of Clinical Investigation, 118(1), 6-14. https://doi.org/10.1172/JCI32483