Antipsychotics in the treatment of autism

David J. Posey, Kimberly A. Stigler, Craig A. Erickson, Christopher J. McDougle

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

Atypical antipsychotics have become indispensable in the treatment of a variety of symptoms in autism. They are frequently used to treat irritability and associated behaviors including aggression and self injury. They may also be efficacious for hyperactivity and stereotyped behavior. This review presents the rationale for the use of this drug class in autism and reviews the most important studies published on this topic to date. Significant adverse effects, including weight gain and the possibility of tardive dyskinesia, are reviewed. Future research directions are discussed.

Original languageEnglish
Pages (from-to)6-14
Number of pages9
JournalJournal of Clinical Investigation
Volume118
Issue number1
DOIs
StatePublished - Jan 2 2008

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Autistic Disorder
Antipsychotic Agents
Stereotyped Behavior
Aggression
Weight Gain
Wounds and Injuries
Pharmaceutical Preparations
Tardive Dyskinesia
Direction compound

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Posey, D. J., Stigler, K. A., Erickson, C. A., & McDougle, C. J. (2008). Antipsychotics in the treatment of autism. Journal of Clinical Investigation, 118(1), 6-14. https://doi.org/10.1172/JCI32483

Antipsychotics in the treatment of autism. / Posey, David J.; Stigler, Kimberly A.; Erickson, Craig A.; McDougle, Christopher J.

In: Journal of Clinical Investigation, Vol. 118, No. 1, 02.01.2008, p. 6-14.

Research output: Contribution to journalArticle

Posey, DJ, Stigler, KA, Erickson, CA & McDougle, CJ 2008, 'Antipsychotics in the treatment of autism', Journal of Clinical Investigation, vol. 118, no. 1, pp. 6-14. https://doi.org/10.1172/JCI32483
Posey DJ, Stigler KA, Erickson CA, McDougle CJ. Antipsychotics in the treatment of autism. Journal of Clinical Investigation. 2008 Jan 2;118(1):6-14. https://doi.org/10.1172/JCI32483
Posey, David J. ; Stigler, Kimberly A. ; Erickson, Craig A. ; McDougle, Christopher J. / Antipsychotics in the treatment of autism. In: Journal of Clinical Investigation. 2008 ; Vol. 118, No. 1. pp. 6-14.
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