Anxiety but not social stressors predict 12-month depression and pain severity

Matthew Bair, Ellen L. Poleshuck, Jingwei Wu, Erin K. Krebs, Teresa Damush, Wanzhu Tu, Kurt Kroenke

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

To determine whether baseline anxiety and social stressors as well their early change (first 3 months) predict 12-month depression and pain severity. METHODS:: We analyzed data from the Stepped Care for Affective Disorders and Musculoskeletal Pain study, a randomized clinical trial of a combined medication-behavioral intervention for primary care patients with chronic musculoskeletal pain and depression. Using multivariable linear regression modeling, we examined the independent association of baseline anxiety and social stressors with depression and pain severity at 12 months. In addition, we modeled whether changes in anxiety and social stressors predicted 12-month depression and pain severity. RESULTS:: Overall, the sample (N=250) was 52.8% women with a mean age of 55.5 years, and a racial distribution of 60.4% white, 36.4% black, and 3.2% other. Depression and pain were moderately severe at baseline (mean SCL-20 depression=1.9 and Brief Pain Inventory pain severity=6.15) and similar across intervention and usual care arms. Baseline anxiety symptoms predicted both depression (t score=2.13, P=0.034) and pain severity (t score=2.75, P=0.007) at 12 months. Also, early change in anxiety predicted 12-month depression (t score=-2.47, P=0.014), but not pain. Neither baseline nor early change in social stressors predicted depression or pain severity. CONCLUSIONS:: Anxiety, but not social stressors predict 12-month depression and pain severity. The presence of comorbid anxiety should be considered in the assessment and treatment of patients with musculoskeletal pain and depression, particularly as a factor that may adversely affect treatment response.

Original languageEnglish
Pages (from-to)95-101
Number of pages7
JournalClinical Journal of Pain
Volume29
Issue number2
DOIs
StatePublished - Feb 2013

Fingerprint

Anxiety
Depression
Pain
Musculoskeletal Pain
Mood Disorders
Chronic Pain
Linear Models
Primary Health Care
Randomized Controlled Trials
Equipment and Supplies
Therapeutics

Keywords

  • anxiety
  • Depression
  • pain
  • primary care
  • stress

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology

Cite this

Anxiety but not social stressors predict 12-month depression and pain severity. / Bair, Matthew; Poleshuck, Ellen L.; Wu, Jingwei; Krebs, Erin K.; Damush, Teresa; Tu, Wanzhu; Kroenke, Kurt.

In: Clinical Journal of Pain, Vol. 29, No. 2, 02.2013, p. 95-101.

Research output: Contribution to journalArticle

@article{21962c229b2c4d49a69a39e531dbf20b,
title = "Anxiety but not social stressors predict 12-month depression and pain severity",
abstract = "To determine whether baseline anxiety and social stressors as well their early change (first 3 months) predict 12-month depression and pain severity. METHODS:: We analyzed data from the Stepped Care for Affective Disorders and Musculoskeletal Pain study, a randomized clinical trial of a combined medication-behavioral intervention for primary care patients with chronic musculoskeletal pain and depression. Using multivariable linear regression modeling, we examined the independent association of baseline anxiety and social stressors with depression and pain severity at 12 months. In addition, we modeled whether changes in anxiety and social stressors predicted 12-month depression and pain severity. RESULTS:: Overall, the sample (N=250) was 52.8{\%} women with a mean age of 55.5 years, and a racial distribution of 60.4{\%} white, 36.4{\%} black, and 3.2{\%} other. Depression and pain were moderately severe at baseline (mean SCL-20 depression=1.9 and Brief Pain Inventory pain severity=6.15) and similar across intervention and usual care arms. Baseline anxiety symptoms predicted both depression (t score=2.13, P=0.034) and pain severity (t score=2.75, P=0.007) at 12 months. Also, early change in anxiety predicted 12-month depression (t score=-2.47, P=0.014), but not pain. Neither baseline nor early change in social stressors predicted depression or pain severity. CONCLUSIONS:: Anxiety, but not social stressors predict 12-month depression and pain severity. The presence of comorbid anxiety should be considered in the assessment and treatment of patients with musculoskeletal pain and depression, particularly as a factor that may adversely affect treatment response.",
keywords = "anxiety, Depression, pain, primary care, stress",
author = "Matthew Bair and Poleshuck, {Ellen L.} and Jingwei Wu and Krebs, {Erin K.} and Teresa Damush and Wanzhu Tu and Kurt Kroenke",
year = "2013",
month = "2",
doi = "10.1097/AJP.0b013e3182652ee9",
language = "English",
volume = "29",
pages = "95--101",
journal = "Clinical Journal of Pain",
issn = "0749-8047",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Anxiety but not social stressors predict 12-month depression and pain severity

AU - Bair, Matthew

AU - Poleshuck, Ellen L.

AU - Wu, Jingwei

AU - Krebs, Erin K.

AU - Damush, Teresa

AU - Tu, Wanzhu

AU - Kroenke, Kurt

PY - 2013/2

Y1 - 2013/2

N2 - To determine whether baseline anxiety and social stressors as well their early change (first 3 months) predict 12-month depression and pain severity. METHODS:: We analyzed data from the Stepped Care for Affective Disorders and Musculoskeletal Pain study, a randomized clinical trial of a combined medication-behavioral intervention for primary care patients with chronic musculoskeletal pain and depression. Using multivariable linear regression modeling, we examined the independent association of baseline anxiety and social stressors with depression and pain severity at 12 months. In addition, we modeled whether changes in anxiety and social stressors predicted 12-month depression and pain severity. RESULTS:: Overall, the sample (N=250) was 52.8% women with a mean age of 55.5 years, and a racial distribution of 60.4% white, 36.4% black, and 3.2% other. Depression and pain were moderately severe at baseline (mean SCL-20 depression=1.9 and Brief Pain Inventory pain severity=6.15) and similar across intervention and usual care arms. Baseline anxiety symptoms predicted both depression (t score=2.13, P=0.034) and pain severity (t score=2.75, P=0.007) at 12 months. Also, early change in anxiety predicted 12-month depression (t score=-2.47, P=0.014), but not pain. Neither baseline nor early change in social stressors predicted depression or pain severity. CONCLUSIONS:: Anxiety, but not social stressors predict 12-month depression and pain severity. The presence of comorbid anxiety should be considered in the assessment and treatment of patients with musculoskeletal pain and depression, particularly as a factor that may adversely affect treatment response.

AB - To determine whether baseline anxiety and social stressors as well their early change (first 3 months) predict 12-month depression and pain severity. METHODS:: We analyzed data from the Stepped Care for Affective Disorders and Musculoskeletal Pain study, a randomized clinical trial of a combined medication-behavioral intervention for primary care patients with chronic musculoskeletal pain and depression. Using multivariable linear regression modeling, we examined the independent association of baseline anxiety and social stressors with depression and pain severity at 12 months. In addition, we modeled whether changes in anxiety and social stressors predicted 12-month depression and pain severity. RESULTS:: Overall, the sample (N=250) was 52.8% women with a mean age of 55.5 years, and a racial distribution of 60.4% white, 36.4% black, and 3.2% other. Depression and pain were moderately severe at baseline (mean SCL-20 depression=1.9 and Brief Pain Inventory pain severity=6.15) and similar across intervention and usual care arms. Baseline anxiety symptoms predicted both depression (t score=2.13, P=0.034) and pain severity (t score=2.75, P=0.007) at 12 months. Also, early change in anxiety predicted 12-month depression (t score=-2.47, P=0.014), but not pain. Neither baseline nor early change in social stressors predicted depression or pain severity. CONCLUSIONS:: Anxiety, but not social stressors predict 12-month depression and pain severity. The presence of comorbid anxiety should be considered in the assessment and treatment of patients with musculoskeletal pain and depression, particularly as a factor that may adversely affect treatment response.

KW - anxiety

KW - Depression

KW - pain

KW - primary care

KW - stress

UR - http://www.scopus.com/inward/record.url?scp=84872088504&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84872088504&partnerID=8YFLogxK

U2 - 10.1097/AJP.0b013e3182652ee9

DO - 10.1097/AJP.0b013e3182652ee9

M3 - Article

C2 - 23183264

AN - SCOPUS:84872088504

VL - 29

SP - 95

EP - 101

JO - Clinical Journal of Pain

JF - Clinical Journal of Pain

SN - 0749-8047

IS - 2

ER -