Abstract
To assess the reported association between colonic angiodysplasia and aortic stenosis, we performed a quantitative and methodologic analysis of the literature. In four controlled studies that support an association between aortic stenosis and idiopathic gastrointestinal bleeding there are major methodologic deficiencies including the following: nonblinded data collection, noncomparable diagnostic examination, nonblinded ascertainment of exposure, and noncomparable demographic susceptibility. None of the studies directly assesses angiodysplasia. Additional case reports about aortic valve replacement used to treat bleeding from angiodysplasia are limited in number and in duration of follow-up. We conclude that the existing literature does not demonstrate an association between aortic stenosis and angiodysplasia. Further controlled evaluation of this topic would be used.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1670-1676 |
| Number of pages | 7 |
| Journal | Gastroenterology |
| Volume | 95 |
| Issue number | 6 |
| State | Published - 1988 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Gastroenterology
Cite this
Aortic stenosis, idiopathic gastrointestinal bleeding, and angiodysplasia : Is there and association? A methodologic critique of the literature. / Imperiale, Thomas; Ransohoff, D. F.
In: Gastroenterology, Vol. 95, No. 6, 1988, p. 1670-1676.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Aortic stenosis, idiopathic gastrointestinal bleeding, and angiodysplasia
T2 - Is there and association? A methodologic critique of the literature
AU - Imperiale, Thomas
AU - Ransohoff, D. F.
PY - 1988
Y1 - 1988
N2 - To assess the reported association between colonic angiodysplasia and aortic stenosis, we performed a quantitative and methodologic analysis of the literature. In four controlled studies that support an association between aortic stenosis and idiopathic gastrointestinal bleeding there are major methodologic deficiencies including the following: nonblinded data collection, noncomparable diagnostic examination, nonblinded ascertainment of exposure, and noncomparable demographic susceptibility. None of the studies directly assesses angiodysplasia. Additional case reports about aortic valve replacement used to treat bleeding from angiodysplasia are limited in number and in duration of follow-up. We conclude that the existing literature does not demonstrate an association between aortic stenosis and angiodysplasia. Further controlled evaluation of this topic would be used.
AB - To assess the reported association between colonic angiodysplasia and aortic stenosis, we performed a quantitative and methodologic analysis of the literature. In four controlled studies that support an association between aortic stenosis and idiopathic gastrointestinal bleeding there are major methodologic deficiencies including the following: nonblinded data collection, noncomparable diagnostic examination, nonblinded ascertainment of exposure, and noncomparable demographic susceptibility. None of the studies directly assesses angiodysplasia. Additional case reports about aortic valve replacement used to treat bleeding from angiodysplasia are limited in number and in duration of follow-up. We conclude that the existing literature does not demonstrate an association between aortic stenosis and angiodysplasia. Further controlled evaluation of this topic would be used.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024244817&partnerID=8YFLogxK
M3 - Article
VL - 95
SP - 1670
EP - 1676
JO - Gastroenterology
JF - Gastroenterology
SN - 0016-5085
IS - 6
ER -