Application of scanning electron microscopy to kidney development and nephron maturation

A. P. Evan, V. H. Gattone, P. M. Blomgren

Research output: Contribution to journalArticle

11 Scopus citations


Canine mesonephros and metanephros were examined, focusing on the structure of the nephron from each and the maturation of the different cell types found in the metanephric nephron. The glomerular visceral epithelium initially had a columnar shape which was modified into a cuboidal sheet possessing numerous slender foot processes. The endothelium began as a double layer with minimal fenestrae. With maturation, a single cell layer was formed possessing many large fenestrae. The maturation of the proximal tubule was documented by changes in the apical microvilli, and the foldings of the lateral and basal cell surfaces.

Original languageEnglish (US)
Pages (from-to)455-473
Number of pages19
JournalScanning electron microscopy
Issue number1
StatePublished - Dec 1 1984

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Biophysics

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