Are statins associated with decreased tooth loss in chronic periodontitis?

Barry G. Saver, Philippe P. Hujoel, Joana Cunha-Cruz, Gerardo Maupome

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Aim: To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis. Material and Methods: We evaluated administrative health plan data from 1996 to 2002 covering dental and periodontal treatment utilization, dental extractions, and prescription medication fills of 12,631 adults aged 48-64 in 2002. With tooth loss as the outcome, we evaluated a number of different patterns of statin prescription across time in multivariate generalized linear models. Results: Unadjusted, statin use was associated with increased tooth loss. After adjustment for potential confounders, there was no suggestion of either increased or decreased tooth loss associated with statin use. Conclusions: Statin use was not associated with either a decreased or an increased risk of tooth loss.

Original languageEnglish (US)
Pages (from-to)214-219
Number of pages6
JournalJournal of Clinical Periodontology
Volume34
Issue number3
DOIs
StatePublished - Mar 2007

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Hydroxymethylglutaryl-CoA Reductase Inhibitors
Tooth Loss
Chronic Periodontitis
Prescriptions
Tooth Extraction
Linear Models
Tooth
Health

Keywords

  • Cohort studies
  • Hydroxymethylglutaryl-CoA reductase inhibitors
  • Periodontal diseases
  • Periodontal diseases/drug therapy
  • Statins
  • Tooth loss

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Are statins associated with decreased tooth loss in chronic periodontitis? / Saver, Barry G.; Hujoel, Philippe P.; Cunha-Cruz, Joana; Maupome, Gerardo.

In: Journal of Clinical Periodontology, Vol. 34, No. 3, 03.2007, p. 214-219.

Research output: Contribution to journalArticle

Saver, Barry G. ; Hujoel, Philippe P. ; Cunha-Cruz, Joana ; Maupome, Gerardo. / Are statins associated with decreased tooth loss in chronic periodontitis?. In: Journal of Clinical Periodontology. 2007 ; Vol. 34, No. 3. pp. 214-219.
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