Are statins associated with decreased tooth loss in chronic periodontitis?

Barry G. Saver, Philippe P. Hujoel, Joana Cunha-Cruz, Gerardo Maupomé

Research output: Contribution to journalArticle

26 Scopus citations


Aim: To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis. Material and Methods: We evaluated administrative health plan data from 1996 to 2002 covering dental and periodontal treatment utilization, dental extractions, and prescription medication fills of 12,631 adults aged 48-64 in 2002. With tooth loss as the outcome, we evaluated a number of different patterns of statin prescription across time in multivariate generalized linear models. Results: Unadjusted, statin use was associated with increased tooth loss. After adjustment for potential confounders, there was no suggestion of either increased or decreased tooth loss associated with statin use. Conclusions: Statin use was not associated with either a decreased or an increased risk of tooth loss.

Original languageEnglish (US)
Pages (from-to)214-219
Number of pages6
JournalJournal of Clinical Periodontology
Issue number3
StatePublished - Mar 1 2007


  • Cohort studies
  • Hydroxymethylglutaryl-CoA reductase inhibitors
  • Periodontal diseases
  • Periodontal diseases/drug therapy
  • Statins
  • Tooth loss

ASJC Scopus subject areas

  • Periodontics

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