Arteriovenous malformation masquerading as a bladder tumor: A case report

Quan Zhou, Hong Chang, Lei Yang, Jixin Zhang, Hongyu Zhao, Lisha Wang, Antonio Lopez-Beltran, Rodolfo Montironi, Darrell D. Davidson, Liang Cheng

Research output: Contribution to journalArticle


BACKGROUND: Arteriovenous malformation (AVM) of the urinary bladder is an extremely rare benign vascular lesion. The clinical significance of bladder AVM lies in its presentation with painless hematuria and a hyperemic sessile bladder wall mass. CASE REPORT: A 47-year-old man presented with ir-ritative symptoms and hematuria. Cystoscopically the lesion appeared as an erythematous, broad-based mass obscuring the right ureteral orifice. The patient underwent cystoprostatectomy for suspected mass lesion. His-tologically the bladder tumor was composed of numerous malformed blood vessels of various calibers with myxoid degeneration. Immunohistochemically the bland endothelial cells lining in the vessels were reactive for markers of CD31 and CD34. Ki67 index was <1%. The patient was free of disease 24 months after surgery. CONCLUSION: Our findings broaden the morphologic spectrum of bladder arteriovenous malformation and emphasize its deceptive presentation.

Original languageEnglish (US)
Pages (from-to)322-325
Number of pages4
JournalAnalytical and Quantitative Cytology and Histology
Issue number5
StatePublished - Jan 1 2015


  • AVM
  • Arteriovenous malformations
  • Bladder
  • Differential diagnosis
  • Urinary bladder
  • Vascular lesions

ASJC Scopus subject areas

  • Anatomy
  • Histology

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    Zhou, Q., Chang, H., Yang, L., Zhang, J., Zhao, H., Wang, L., Lopez-Beltran, A., Montironi, R., Davidson, D. D., & Cheng, L. (2015). Arteriovenous malformation masquerading as a bladder tumor: A case report. Analytical and Quantitative Cytology and Histology, 37(5), 322-325.