Assessment of left ventricular function: Comparison of cardiac multidetector-row computed tomography with two-dimension standard echocardiography for assessment of left ventricular function

Darpan Bansal, Robin M. Singh, Mrinalini Sarkar, Ravi Sureddi, Kelly C. Mcbreen, Timothy Griffis, Anjan Sinha, Jawahar L. Mehta

Research output: Contribution to journalArticle

28 Scopus citations


Objective: To compare global Left Ventricular (LV) systolic function assessment by 16-detector row Computed Tomography (MDCT) with Two-Dimensional Standard Echocardiography (2DSE) in a routine cardiology practice setting and to ascertain the degree of correlation between LV volumes and measurements obtained by 2DSE with those measured by MDCT. Methods: In 52 patients with suspected coronary artery disease, a contrast enhanced MDCT study was performed using retrospective gating without dose modulation for better endocardial delineation. Eight phases of the cardiac cycle were analyzed to identify the end-diastolic and end-systolic phases. 2DSE was performed on the same day. Left ventricular systolic and diastolic volumes and ejection fraction were calculated in 4-chamber, 2-chamber and biplane (average of the two) views. Endocardial tracing was used to measure ventricular volumes by area length method for CT and Simpson's method for echocardiography. Results: On MDCT, mean LV ejection fraction (LVEF) in 4-chamber, 2-chamber and biplane views were 58.4 ± 12, 59.3 ± 12 and 59.7 ± 12% respectively. On 2DSE, mean LVEF in 4-chamber, 2-chamber and biplane views were 58 ± 14, 57 ± 16 and 58 ± 13% respectively. LVEF correlated best using the biplane views (r = 0.59 and P < 0.01) compared to 2-chamber (r = 0.57 and P < 0.01) and 4-chamber views (r = 0.32 and P = 0.02). Biplane measurement by these two techniques correlated well for LV volumes in both diastole (r = 0.69 and P < 0.01) and systole (r = 0.73 and P < 0.01), although MDCT consistently gave higher values. Conclusions: MDCT can be a useful tool to measure LVEF while patients are undergoing CT coronary angiography.

Original languageEnglish (US)
Pages (from-to)317-325
Number of pages9
JournalInternational Journal of Cardiovascular Imaging
Issue number3
StatePublished - Dec 1 2008



  • Computed tomography
  • Echocardiography
  • Left ventricular ejection fraction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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