Assessment of wall motion improvement following PTCA in patients with chronic stable angina: Utility of exercise echocardiography

R. Gentile, J. Dillon, M. Frasca, T. Ryan, H. Feigenbaum

Research output: Contribution to journalArticle

Abstract

To assess the efficacy of coronary angioplasty (PTCA) in patients with chronic stable angina, two-dimensional exercise echocardiograms were obtained in 21 patients early before and several days after revascularization. Wall motion index (WMI) was calculated for each examination with the help of digital echocardiography. Before PTCA, typical angina pectoris was present in 90% of patients and 80% of them showed provokable ischemia documented by the comparison of wall motion abnormalities during stress test. The WMI from 1.10 ± 0.12 at rest increased to 1.36 ± 0.25 at peak exercise. Following angioplasty, angina disappeared in the great majority of the study population and the WMI decreased both at rest (1.04 ± 0.06) and during stress (1.09 ± 0.16) with statistical significance (p = 0.002 and 0.001, respectively). Out of 11 patients who had showed a normal exercise test after PTCA and who were followed for a minimum of 1 year, only one had a documented restenosis. The recovery of regional ventricular function was related to the improvement of wall motion supplied by the successful dilated artery, and this finding clearly identified a subset of patients with hibernating myocardium. We conclude that exercise echocardiography, in addition to standard ECG testing, is helpful in assessing the functional severity of myocardial ischemia and in documenting the improvement of regional function following revascularization by coronary angioplasty.

Original languageEnglish (US)
Pages (from-to)53-59
Number of pages7
JournalCardiovascular Imaging
Volume5
Issue number2
StatePublished - Jan 1 1993
Externally publishedYes

Keywords

  • coronary angioplasty
  • exercise echocardiography
  • stable angina
  • wall motion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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