Association of APOE gene with schizophrenia in Chinese: A possible risk factor in times of malnutrition

Wanqing Liu, Gerome Breen, Jiangang Zhang, Sheng Li, Niufan Gu, Guoyin Feng, Shaochun Bai, Tao Shen, Albert Yu, Hong Xue, David St Clair, Lin He

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Five hundred and seventy nine Chinese patients with schizophrenia who met DSMIV criteria for the disorder were genotyped for alleles ε2,3,4 of apolipoprotein E (APOE) gene. All were recruited from inpatients and outpatients attending a large mental health centre in Shanghai. Results were compared to APOE data on 1528 controls drawn from the same area. Major differences in APOE genotype ratios and allele frequencies were observed between the patients and controls. The patients with schizophrenia had highly significantly (p

Original languageEnglish (US)
Pages (from-to)225-230
Number of pages6
JournalSchizophrenia Research
Volume62
Issue number3
DOIs
StatePublished - Aug 1 2003
Externally publishedYes

Fingerprint

Apolipoproteins E
Malnutrition
Schizophrenia
Apolipoprotein E3
Genes
Apolipoprotein E4
Gene Frequency
Inpatients
Mental Health
Outpatients
Alleles
Genotype

Keywords

  • APOE
  • China
  • Fetal and perinatal malnutrition
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

Cite this

Association of APOE gene with schizophrenia in Chinese : A possible risk factor in times of malnutrition. / Liu, Wanqing; Breen, Gerome; Zhang, Jiangang; Li, Sheng; Gu, Niufan; Feng, Guoyin; Bai, Shaochun; Shen, Tao; Yu, Albert; Xue, Hong; St Clair, David; He, Lin.

In: Schizophrenia Research, Vol. 62, No. 3, 01.08.2003, p. 225-230.

Research output: Contribution to journalArticle

Liu, W, Breen, G, Zhang, J, Li, S, Gu, N, Feng, G, Bai, S, Shen, T, Yu, A, Xue, H, St Clair, D & He, L 2003, 'Association of APOE gene with schizophrenia in Chinese: A possible risk factor in times of malnutrition', Schizophrenia Research, vol. 62, no. 3, pp. 225-230. https://doi.org/10.1016/S0920-9964(02)00384-5
Liu, Wanqing ; Breen, Gerome ; Zhang, Jiangang ; Li, Sheng ; Gu, Niufan ; Feng, Guoyin ; Bai, Shaochun ; Shen, Tao ; Yu, Albert ; Xue, Hong ; St Clair, David ; He, Lin. / Association of APOE gene with schizophrenia in Chinese : A possible risk factor in times of malnutrition. In: Schizophrenia Research. 2003 ; Vol. 62, No. 3. pp. 225-230.
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