Atrial fibrillation: From cell to bedside

Douglas P. Zipes

Research output: Contribution to journalReview article

41 Scopus citations


Atrial fibrillation is the most common sustained tachyarrhythmia and, as such, has become the recent focus of intense clinical and experimental interest. Because of its associated morbidity and mortality, there is a multidisciplinary effort to understand the pathophysiology that may ultimately lead to improved therapeutic options. This review concentrates on three aspects of atrial fibrillation that influence contemporary choices for treatment: an electrophysiologic basis for initiation of atrial fibrillation, anatomic and electrophysiologic remodeling, and concepts regarding its termination or prevention.

Original languageEnglish (US)
Pages (from-to)927-938
Number of pages12
JournalJournal of cardiovascular electrophysiology
Issue number8
StatePublished - Jan 1 1997


  • Autonomics
  • Remodeling
  • Tachycardia-induced cardiomyopathy

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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