Atrial Fibrillation

What are the Targets for Intervention?

John Miller, Jeffrey E. Olgin, Mithilesh Das

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Atrial fibrillation (AF) is a difficult and growing problem in the population. While medical therapy controls symptoms in many patients, a proportion of individuals with this common arrhythmia cannot be optimally managed with drugs alone. However, truly curative therapy for AF has always been one of the "holy grails" of electrophysiology. The surgical maze procedure was the first to offer permanent maintenance of sinus rhythm in patients with AF but subjected the patient to open heart surgery; a catheter-based translation of the maze procedure served as proof of concept that a catheterization technique could be used to treat AF. Subsequent experience has narrowed the electrophysiologist's attention to ablation of triggers of AF, most often residing in the pulmonary veins, rather than requiring more extensive ablation lines to control the arrhythmia. The following discussion deals with the development and current status of techniques for catheter ablation of atrial fibrillation, focusing on determination of appropriate target sites for ablation.

Original languageEnglish
Pages (from-to)249-257
Number of pages9
JournalJournal of Interventional Cardiac Electrophysiology
Volume9
Issue number2
DOIs
StatePublished - Oct 2003

Fingerprint

Atrial Fibrillation
Cardiac Arrhythmias
Catheter Ablation
Pulmonary Veins
Electrophysiology
Catheterization
Thoracic Surgery
Catheters
Maintenance
Therapeutics
Pharmaceutical Preparations
Population

Keywords

  • Atrial fibrillation
  • Catheter ablation
  • Pulmonary vein

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Atrial Fibrillation : What are the Targets for Intervention? / Miller, John; Olgin, Jeffrey E.; Das, Mithilesh.

In: Journal of Interventional Cardiac Electrophysiology, Vol. 9, No. 2, 10.2003, p. 249-257.

Research output: Contribution to journalArticle

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