Autoimmunity: polyclonal activation or antigen induction?

Research output: Contribution to journalArticle

75 Scopus citations


Two conflicting views of autoimmunity picture autoantibody production as the result of either polyclonal activation or the stimulation of a response to a specific autoantigen. Here, Roman Dziarski summarizes the evidence supporting each model and highlights the inability of either model alone to account satisfactorily for autoimmunity. He proposes the consolidation of the two views into one unified theory.

Original languageEnglish (US)
Pages (from-to)340-342
Number of pages3
JournalImmunology Today
Issue number11
StatePublished - 1988

ASJC Scopus subject areas

  • Immunology

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