Autolysis of Escherichia coli and Bacillus subtilis cells in low gravity

M. A. Kacena, E. E. Smith, P. Todd

Research output: Contribution to journalArticle

16 Scopus citations


The role of gravity in the autolysis of Bacillus subtilis and Escherichia coli was studied by growing cells on Earth and in microgravity on Space Station Mir. Autolysis analysis was completed by examining the death phase or exponential decay of cells for approximately 4 months following the stationary phase. Consistent with published findings, the stationary-phase cell population was 170% and 90% higher in flight B. subtilis and E. coli cultures, respectively, than in ground cultures. Although both flight autolysis curves began at higher cell densities than control curves, the rate of autolysis in flight cultures was identical to that of their respective ground control rates.

Original languageEnglish (US)
Pages (from-to)437-439
Number of pages3
JournalApplied Microbiology and Biotechnology
Issue number3
StatePublished - Sep 1 1999
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

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