B-cell lymphoma: Suppressing a tumor suppressor

Research output: Contribution to journalShort survey

3 Citations (Scopus)

Abstract

The BCL-6 oncogene can downregulate expression of the p53 tumor suppressor gene in B cell lymphoma. This pathway probably exists to protect normal germinal-center B cells from apoptosis induced by DNA mutations.

Original languageEnglish (US)
Number of pages1
JournalNature Medicine
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2005

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Germinal Center
B-Cell Lymphoma
Tumor Suppressor Genes
Oncogenes
Tumors
B-Lymphocytes
Down-Regulation
Cells
Apoptosis
Mutation
DNA
Neoplasms
Genes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

B-cell lymphoma : Suppressing a tumor suppressor. / Dent, Alexander.

In: Nature Medicine, Vol. 11, No. 1, 01.01.2005.

Research output: Contribution to journalShort survey

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