Bacterial growth in space flight: Logistic growth curve parameters for Escherichia coli and Bacillus subtilis

M. A. Kacena, G. A. Merrell, B. Manfredi, E. E. Smith, D. M. Klaus, P. Todd

Research output: Contribution to journalArticle

88 Scopus citations


Previous investigations have reported that bacterial suspension cultures grow to higher stationary concentrations in space flight than on Earth; however, none of these investigations included extensive ground controls under varied inertial conditions. This study includes extensive controls and cell-growth data taken at several times during lag phase, log phase, and stationary phase of Escherichia coli and Bacillus subtilis. The Marquardt- Levenberg, least-squares fitting algorithm was used to calculate kinetic growth parameters from the logistic bacterial growth equations for space- flight and control growth curves. Space-flight cultures grew to higher stationary-phase concentrations and had shorter lag-phase durations. Also, evidence was found for increased exponential growth rate in space.

Original languageEnglish (US)
Pages (from-to)229-234
Number of pages6
JournalApplied Microbiology and Biotechnology
Issue number2
StatePublished - Mar 13 1999


ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

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