Bacterial meningitis

Karen L. Roos, Diederik D.E. Van Beek

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Bacterial meningitis is a neurological emergency. Empiric antimicrobial and adjunctive therapy should be initiated as soon as a single set of blood cultures has been obtained. Clinical signs suggestive of bacterial meningitis include fever, headache, meningismus, vomiting, photophobia, and an altered level of consciousness. The peripheral white blood cell count with a left shift, an elevated serum procalcitonin and C-reactive protein, and a CSF pleocytosis with a predominance of polymorphonuclear leukocytes, and a decreased glucose concentration are predictive of bacterial meningitis. Patients with documented bacterial meningitis and those in whom the diagnosis is a strong possibility should be admitted to the intensive care unit. Timely recognition of bacterial meningitis and initiation of therapy are critical to outcome (Aronin et al., 1998; Miner et al., 2001; Proulx et al., 2005).

Original languageEnglish (US)
Pages (from-to)51-63
Number of pages13
JournalHandbook of Clinical Neurology
Volume96
Issue numberC
DOIs
StatePublished - Jan 1 2010

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Bacterial meningitis'. Together they form a unique fingerprint.

  • Cite this