Bariatric surgery outcomes in HIV-infected subjects: A case series

Henry Selke, Steven Norris, Danielle Osterholzer, Kenneth Fife, Barbara Derose, Samir Gupta

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Obesity is now a common problem among HIV-infected patients receiving antiretroviral therapy (ART). Gastric bypass surgery may be an option for some patients who have failed diet and therapeutic lifestyle changes, changes in ART or other treatment modalities for HIV/ART-related lipohypertrophy and obesity. However, few data are available regarding HIV-related outcomes after such surgery and its impact on ART tolerability. We present here a case series of seven subjects with HIV infection who underwent bariatric surgery. Viral suppression was maintained in five of the six subjects who were receiving ART prior to surgery, including three subjects who experienced surgical complications. The median (range) decrease in body mass index (BMI) postoperatively was 10kg/m2 (6-28?kg/m2). Improvements were also seen in serum lipid fractions with median (range) changes in total cholesterol of -19mg/dL (-61 to +3mg/dL) and triglycerides of -185?mg/dL (-739 to +35mg/dL). Four of the subjects had a reduction in their metabolic medication prescriptions postoperatively. Three of the subjects experienced postsurgical complications. Based on our experience, bariatric surgery may provide an effective treatment modality for obesity and its related comorbidities in the HIV-infected population while not sacrificing virologic suppression. Larger studies are needed to verify these results, especially in regards to surgical complications.

Original languageEnglish
Pages (from-to)545-550
Number of pages6
JournalAIDS Patient Care and STDs
Volume24
Issue number9
DOIs
StatePublished - Sep 1 2010

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Bariatric Surgery
HIV
Obesity
Therapeutics
Gastric Bypass
HIV Infections
Prescriptions
Life Style
Comorbidity
Triglycerides
Body Mass Index
Cholesterol
Diet
Lipids
Serum

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Bariatric surgery outcomes in HIV-infected subjects : A case series. / Selke, Henry; Norris, Steven; Osterholzer, Danielle; Fife, Kenneth; Derose, Barbara; Gupta, Samir.

In: AIDS Patient Care and STDs, Vol. 24, No. 9, 01.09.2010, p. 545-550.

Research output: Contribution to journalArticle

Selke, Henry ; Norris, Steven ; Osterholzer, Danielle ; Fife, Kenneth ; Derose, Barbara ; Gupta, Samir. / Bariatric surgery outcomes in HIV-infected subjects : A case series. In: AIDS Patient Care and STDs. 2010 ; Vol. 24, No. 9. pp. 545-550.
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