Basal ganglia pathology in schizophrenia and tardive dyskinesia: An MRI quantitative study

Ahmed M. Elkashef, Robert W. Buchanan, Fouad Gellad, Robert C. Munson, Alan Breier

Research output: Contribution to journalArticle

77 Scopus citations

Abstract

Magnetic resonance imaging was used to measure the volumes of the caudate, putamen, and globus pallidus of 25 schizophrenic patients (17 men and eight women) and 26 age- and sex-matched comparison subjects (18 men and eight women). Schizophrenic patients had significantly larger right and left globus pallidus and right putamen volumes than comparison subjects. There were no significant differences between schizophrenic patients with and without persistent tardive dyskinesia in the volume of any of the three structures.

Original languageEnglish (US)
Pages (from-to)752-755
Number of pages4
JournalAmerican Journal of Psychiatry
Volume151
Issue number5
DOIs
StatePublished - May 1994

ASJC Scopus subject areas

  • Psychiatry and Mental health

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