Behavioral and EEG responses to alcohol in nonalcoholic men with a family history of alcoholism

Richard F. Kaplan, Victor M. Hesselbrock, Sean O'Connor, Nancy Depalma

Research output: Contribution to journalArticle

53 Scopus citations


1. 1. Behavioral and EEG responses were examined in nonalcoholic males with (FH+) and without (FH-) a family history of alcoholism following the consumption of a placebo and real beer. 2. 2. FH+ subjects were less confident of being able to resist another drink following consumption of the placebo and reported higher taste ratings and feeling more intoxicated immediately following ethanol consumption than FH- subjects. 3. 3. Both groups showed increases in EEG alpha activity (9-12Hz) following alcohol consumption. 4. Alpha activity was positively associated with desire to drink in the FH+ group before and after consumption, but was positively associated with perceived intoxication in the FH- group only after consumption.

Original languageEnglish (US)
Pages (from-to)873-885
Number of pages13
JournalProgress in Neuropsychopharmacology and Biological Psychiatry
Issue number6
StatePublished - 1988
Externally publishedYes


  • children of alcoholics
  • familial alcoholism
  • genetic risk
  • response to alcohol

ASJC Scopus subject areas

  • Pharmacology
  • Biological Psychiatry

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