Benign and low-grade papillary lesions of the urinary bladder: A review of the papilloma-papillary carcinoma controversy, and a report of five typical papillomas

John N. Eble, Robert H. Young

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37 Scopus citations

Abstract

The controversial topic concerning the most appropriate nomenclature for low-grade papillary lesions of the urinary bladder is reviewed on the basis of the literature and the authors' experiences. This undertaking was prompted by a recent report in which use of the designation "papilloma" was advocated for lesions that generally had been diagnosed as grade 1 papillary urothelial carcinoma. The literature indicates that 10% to 20% of patients with a noninvasive low-grade papillary tumor of the bladder will later have invasive bladder cancer. This significant outcome in a minority of such patients warrants very careful follow-up for the group as a whole, Irrespective of the terminology used. The authors contrast the features of papillary urothelial carcinoma with a series of five cases, which they interpret as true papillomas. They believe that these low-grade papillary lesions can be distinguished from true papillomas and do not favor a change in terminology. Some of the problems in the evaluation of Inverted papilloma and inverting urothelial carcinoma are briefly reviewed as are other selected papillary lesions of the urinary bladder.

Original languageEnglish (US)
Pages (from-to)351-371
Number of pages21
JournalSeminars in Diagnostic Pathology
Volume6
Issue number4
StatePublished - Nov 1989

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Keywords

  • carcinoma
  • papilloma
  • Urinary bladder
  • urothelium

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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