Abstract
Benign prostatic hyperplasia (BPH) and prostate cancer are conditions commonly affecting the prostate gland in aging men. Prior epidemiological studies investigating potential associations between the two have resulted in conflicting data. Recent morphological studies have demonstrated the occurrence of a subset of prostate cancers as arising in the transition zone of the gland, the same region where BPH occurs. A morphologic lesion, atypical adenomatous hyperplasia (AAH), providing a possible link between cancer and BPH has been described. Biological studies of this potential precursor lesion are not yet available, but will be essential in order to further investigate this possible association.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 415-418 |
| Number of pages | 4 |
| Journal | In Vivo |
| Volume | 8 |
| Issue number | 3 |
| State | Published - 1994 |
| Externally published | Yes |
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Keywords
- atypical adenomatous hyperplasia
- benign prostatic hyperplasia
- premalignant lesion
- prostate
ASJC Scopus subject areas
- Medicine(all)
Cite this
Benign prostatic hyperplasia : Is it a premalignant lesion? / Grignon, David; Sakr, W.
In: In Vivo, Vol. 8, No. 3, 1994, p. 415-418.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Benign prostatic hyperplasia
T2 - Is it a premalignant lesion?
AU - Grignon, David
AU - Sakr, W.
PY - 1994
Y1 - 1994
N2 - Benign prostatic hyperplasia (BPH) and prostate cancer are conditions commonly affecting the prostate gland in aging men. Prior epidemiological studies investigating potential associations between the two have resulted in conflicting data. Recent morphological studies have demonstrated the occurrence of a subset of prostate cancers as arising in the transition zone of the gland, the same region where BPH occurs. A morphologic lesion, atypical adenomatous hyperplasia (AAH), providing a possible link between cancer and BPH has been described. Biological studies of this potential precursor lesion are not yet available, but will be essential in order to further investigate this possible association.
AB - Benign prostatic hyperplasia (BPH) and prostate cancer are conditions commonly affecting the prostate gland in aging men. Prior epidemiological studies investigating potential associations between the two have resulted in conflicting data. Recent morphological studies have demonstrated the occurrence of a subset of prostate cancers as arising in the transition zone of the gland, the same region where BPH occurs. A morphologic lesion, atypical adenomatous hyperplasia (AAH), providing a possible link between cancer and BPH has been described. Biological studies of this potential precursor lesion are not yet available, but will be essential in order to further investigate this possible association.
KW - atypical adenomatous hyperplasia
KW - benign prostatic hyperplasia
KW - premalignant lesion
KW - prostate
UR - http://www.scopus.com/inward/record.url?scp=0027937513&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027937513&partnerID=8YFLogxK
M3 - Article
VL - 8
SP - 415
EP - 418
JO - In Vivo
JF - In Vivo
SN - 0258-851X
IS - 3
ER -