Benign prostatic hyperplasia: Is it a premalignant lesion?

David Grignon, W. Sakr

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Benign prostatic hyperplasia (BPH) and prostate cancer are conditions commonly affecting the prostate gland in aging men. Prior epidemiological studies investigating potential associations between the two have resulted in conflicting data. Recent morphological studies have demonstrated the occurrence of a subset of prostate cancers as arising in the transition zone of the gland, the same region where BPH occurs. A morphologic lesion, atypical adenomatous hyperplasia (AAH), providing a possible link between cancer and BPH has been described. Biological studies of this potential precursor lesion are not yet available, but will be essential in order to further investigate this possible association.

Original languageEnglish (US)
Pages (from-to)415-418
Number of pages4
JournalIn Vivo
Volume8
Issue number3
StatePublished - 1994
Externally publishedYes

Fingerprint

Prostatic Hyperplasia
Prostatic Neoplasms
Aging of materials
Hyperplasia
Epidemiologic Studies
Prostate
Neoplasms

Keywords

  • atypical adenomatous hyperplasia
  • benign prostatic hyperplasia
  • premalignant lesion
  • prostate

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Benign prostatic hyperplasia : Is it a premalignant lesion? / Grignon, David; Sakr, W.

In: In Vivo, Vol. 8, No. 3, 1994, p. 415-418.

Research output: Contribution to journalArticle

Grignon, D & Sakr, W 1994, 'Benign prostatic hyperplasia: Is it a premalignant lesion?', In Vivo, vol. 8, no. 3, pp. 415-418.
Grignon, David ; Sakr, W. / Benign prostatic hyperplasia : Is it a premalignant lesion?. In: In Vivo. 1994 ; Vol. 8, No. 3. pp. 415-418.
@article{c5839ce2aaa14d4c8ac7b7cabcf013d2,
title = "Benign prostatic hyperplasia: Is it a premalignant lesion?",
abstract = "Benign prostatic hyperplasia (BPH) and prostate cancer are conditions commonly affecting the prostate gland in aging men. Prior epidemiological studies investigating potential associations between the two have resulted in conflicting data. Recent morphological studies have demonstrated the occurrence of a subset of prostate cancers as arising in the transition zone of the gland, the same region where BPH occurs. A morphologic lesion, atypical adenomatous hyperplasia (AAH), providing a possible link between cancer and BPH has been described. Biological studies of this potential precursor lesion are not yet available, but will be essential in order to further investigate this possible association.",
keywords = "atypical adenomatous hyperplasia, benign prostatic hyperplasia, premalignant lesion, prostate",
author = "David Grignon and W. Sakr",
year = "1994",
language = "English (US)",
volume = "8",
pages = "415--418",
journal = "In Vivo",
issn = "0258-851X",
publisher = "International Institute of Anticancer Research",
number = "3",

}

TY - JOUR

T1 - Benign prostatic hyperplasia

T2 - Is it a premalignant lesion?

AU - Grignon, David

AU - Sakr, W.

PY - 1994

Y1 - 1994

N2 - Benign prostatic hyperplasia (BPH) and prostate cancer are conditions commonly affecting the prostate gland in aging men. Prior epidemiological studies investigating potential associations between the two have resulted in conflicting data. Recent morphological studies have demonstrated the occurrence of a subset of prostate cancers as arising in the transition zone of the gland, the same region where BPH occurs. A morphologic lesion, atypical adenomatous hyperplasia (AAH), providing a possible link between cancer and BPH has been described. Biological studies of this potential precursor lesion are not yet available, but will be essential in order to further investigate this possible association.

AB - Benign prostatic hyperplasia (BPH) and prostate cancer are conditions commonly affecting the prostate gland in aging men. Prior epidemiological studies investigating potential associations between the two have resulted in conflicting data. Recent morphological studies have demonstrated the occurrence of a subset of prostate cancers as arising in the transition zone of the gland, the same region where BPH occurs. A morphologic lesion, atypical adenomatous hyperplasia (AAH), providing a possible link between cancer and BPH has been described. Biological studies of this potential precursor lesion are not yet available, but will be essential in order to further investigate this possible association.

KW - atypical adenomatous hyperplasia

KW - benign prostatic hyperplasia

KW - premalignant lesion

KW - prostate

UR - http://www.scopus.com/inward/record.url?scp=0027937513&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027937513&partnerID=8YFLogxK

M3 - Article

C2 - 7528557

AN - SCOPUS:0027937513

VL - 8

SP - 415

EP - 418

JO - In Vivo

JF - In Vivo

SN - 0258-851X

IS - 3

ER -