Benign vascular tumors, cysts, and pseudocysts of the adrenal gland: a contemporary multi-institutional clinicopathological analysis of 55 cases

Wei Zheng, Kar Ming Fung, Liang Cheng, Adeboye O. Osunkoya

Research output: Contribution to journalArticle

1 Scopus citations


Benign adrenal vascular tumors, cysts, and pseudocysts are a heterogeneous group of relatively uncommon entities that may pose diagnostic challenges radiologically and pathologically. However, there are only a few small cases series systematically characterizing the clinicopathological features of these lesions. We identified 55 cases of benign adrenal vascular tumors, cysts, and pseudocysts (23 pseudocysts, 17 hemangiomas, 8 lymphangiomas, 6 angiomatous endothelial cysts, and 1 arteriovenous malformation) from a multi-institutional urologic pathology database between 2000 and 2017 and retrospectively analyzed their clinicopathological features. We found that these lesions have a female predominance and most are right sided. These lesions may occur simultaneously with other adrenal tumors associated with hormonal hypersecretion. A substantial portion of pseudocysts were semisolid or solid with no fluid collection, mimicking a solid adrenal tumor and resulting in adrenalectomy. In addition, a small proportion of benign vascular lesions may have coexisting epithelial tumors, requiring extensive specimen sampling and thorough microscopic examination.

Original languageEnglish (US)
Pages (from-to)95-102
Number of pages8
JournalHuman pathology
StatePublished - Dec 2018



  • Adrenal gland
  • Angiomatous endothelial cyst
  • Hemangioma
  • Lymphangioma
  • Vascular malformation
  • Vascular tumor, cyst, pseudocyst

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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