Bex, the Bacillus subtilis homolog of the essential Escherichia coli GTPase era, is required for normal cell division and spore formation

Natalie Minkovsky, Arash Zarimani, Vasant K. Chary, Brian H. Johnstone, Bradford S. Powell, Pamela D. Torrance, Donald L. Court, Robert W. Simons, Patrick J. Piggot

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20 Scopus citations

Abstract

The Bacillus subtilis bex gene complemented the defect in an Escherichia coli era mutant. The Bex protein showed 39% identity and 67% similarity to the E. coli Era GTPase. In contrast to era, bex was not essential in all strains. bex mutant cells were elongated and filled with diffuse nucleoid material. They grew slowly and exhibited severely impaired spore formation.

Original languageEnglish (US)
Pages (from-to)6389-6394
Number of pages6
JournalJournal of bacteriology
Volume184
Issue number22
DOIs
StatePublished - Nov 2002

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ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

Cite this

Minkovsky, N., Zarimani, A., Chary, V. K., Johnstone, B. H., Powell, B. S., Torrance, P. D., Court, D. L., Simons, R. W., & Piggot, P. J. (2002). Bex, the Bacillus subtilis homolog of the essential Escherichia coli GTPase era, is required for normal cell division and spore formation. Journal of bacteriology, 184(22), 6389-6394. https://doi.org/10.1128/JB.184.22.6389-6394.2002