Bioactive glass in bone tissue engineering

Mohamed N. Rahaman, Xin Liu, B. Sonny Bal, Delbert E. Day, Lianxiang Bi, Lynda F. Bonewald

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Bioactive glass has several appealing characteristics as a scaffold material for bone tissue engineering. While silicate bioactive glasses (such as 45S5 glass) have been widely investigated over the last few decades, borate bioactive glasses have been attracting considerable interest recently. Borate bioactive glasses convert faster and more completely to a hydroxyapatite-like material in a simulated body fluid than silicate bioactive glasses, and they have been shown to support faster bone formation and enhance angiogenesis. However, borate bioactive glasses show a more rapid degradation in strength than silicate bioactive glasses when immersed in a simulated body fluid or implanted in vivo. Advances in biomaterials processing have resulted in the creation of bioactive glass scaffolds with compressive strength and elastic modulus values in the range of trabecular to cortical bone. This article provides a review of our recent advances in bioactive glasses for the regeneration of loaded and non-loaded bone.

Original languageEnglish (US)
Title of host publicationBiomaterials Science
Subtitle of host publicationProcessing, Properties and Applications II
PublisherAmerican Ceramic Society
Pages73-82
Number of pages10
ISBN (Print)9781118273326
StatePublished - Jan 1 2012
Externally publishedYes
EventNext Generation Biomaterials and Surface Properties of Biomaterials Symposia - Materials Science and Technology 2011 Conference and Exhibition, MS and T 2011 - Columbus, OH, United States
Duration: Oct 16 2011Oct 20 2011

Publication series

NameCeramic Transactions
Volume237
ISSN (Print)1042-1122

Other

OtherNext Generation Biomaterials and Surface Properties of Biomaterials Symposia - Materials Science and Technology 2011 Conference and Exhibition, MS and T 2011
CountryUnited States
CityColumbus, OH
Period10/16/1110/20/11

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ASJC Scopus subject areas

  • Ceramics and Composites
  • Materials Chemistry

Cite this

Rahaman, M. N., Liu, X., Bal, B. S., Day, D. E., Bi, L., & Bonewald, L. F. (2012). Bioactive glass in bone tissue engineering. In Biomaterials Science: Processing, Properties and Applications II (pp. 73-82). (Ceramic Transactions; Vol. 237). American Ceramic Society.