Biochemical Programs of Slowly and Rapidly Growing Human Colon Carcinoma Xenografts

George Weber, May S. Lui, Noemi Prajda, Diana Y. Tzeng, Robert C. Jackson, Eiji Takeda, John N. Eble, Jean C. Hager

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

The purpose of this investigation was to elucidate the enzymic programs of pyrimidine, carbohydrate, and purine metabolism and the pattern of pyrimidine and purine ribonucleotides in two lines of human colon carcinoma xenografts of different growth rates. The slower-growing colon tumor line was well differentiated; the more rapidly growing line was a poorly differentiated one. The carcinoma xenografts were carried in nude (athymic) mice.

Original languageEnglish (US)
Pages (from-to)854-859
Number of pages6
JournalCancer Research
Volume41
Issue number3
StatePublished - Mar 1 1981

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Weber, G., Lui, M. S., Prajda, N., Tzeng, D. Y., Jackson, R. C., Takeda, E., Eble, J. N., & Hager, J. C. (1981). Biochemical Programs of Slowly and Rapidly Growing Human Colon Carcinoma Xenografts. Cancer Research, 41(3), 854-859.