Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development

Meeting Summary

Richard Gorlick, Peter Anderson, Irene Andrulis, Carola Arndt, G. Peter Beardsley, Mark Bernstein, Julia Bridge, Nai Kong Cheung, Jeffrey S. Dome, David Ebb, Thomas Gardner, Mark Gebhardt, Holcombe Grier, Marc Hansen, John Healey, Lee Helman, Janet Hock, Janet Houghton, Peter Houghton, Andrew Huvos & 19 others Chand Khanna, Mark Kieran, Eugenie Kleinerman, Marc Ladanyi, Ching Lau, David Malkin, Neyssa Marina, Paul Meltzer, Paul Meyers, Deborah Schofield, Cindy Schwartz, Malcolm A. Smith, Jeffrey Toretsky, Maria Tsokos, Leonard Wexler, Jon Wigginton, Stephen Withrow, Mason Schoenfeldt, Barry Anderson

Research output: Contribution to journalArticle

138 Citations (Scopus)

Abstract

Childhood osteogenic sarcoma (OS) is a rare bone cancer occurring primarily in adolescents. The North American pediatric cooperative groups have performed a series of clinical treatment trials in this disease over the past several decades, and biology studies of tumor tissue have been an important study component. A meeting was held in Bethesda, Maryland on November 29-30, 2001, sponsored by the NIH Office of Rare Diseases, the Children's Oncology Group, and the National Cancer Institute-Cancer Therapy Evaluation Program with the general objectives: (a) to review the current state of knowledge regarding OS biology; (b) to identify, prioritize, and support the development of biology studies of potential clinical relevance in OS; and (c) to discuss the available tissue resources and the appropriate methods for analysis of OS samples for the conduct of biology studies. This report summarizes the information presented and discussed by the meeting participants.

Original languageEnglish
Pages (from-to)5442-5453
Number of pages12
JournalClinical Cancer Research
Volume9
Issue number15
StatePublished - Nov 15 2003

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Osteosarcoma
Bone Neoplasms
National Cancer Institute (U.S.)
Program Evaluation
Therapeutics
Rare Diseases
Neoplasms
Clinical Trials
Pediatrics

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Gorlick, R., Anderson, P., Andrulis, I., Arndt, C., Beardsley, G. P., Bernstein, M., ... Anderson, B. (2003). Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary. Clinical Cancer Research, 9(15), 5442-5453.

Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development : Meeting Summary. / Gorlick, Richard; Anderson, Peter; Andrulis, Irene; Arndt, Carola; Beardsley, G. Peter; Bernstein, Mark; Bridge, Julia; Cheung, Nai Kong; Dome, Jeffrey S.; Ebb, David; Gardner, Thomas; Gebhardt, Mark; Grier, Holcombe; Hansen, Marc; Healey, John; Helman, Lee; Hock, Janet; Houghton, Janet; Houghton, Peter; Huvos, Andrew; Khanna, Chand; Kieran, Mark; Kleinerman, Eugenie; Ladanyi, Marc; Lau, Ching; Malkin, David; Marina, Neyssa; Meltzer, Paul; Meyers, Paul; Schofield, Deborah; Schwartz, Cindy; Smith, Malcolm A.; Toretsky, Jeffrey; Tsokos, Maria; Wexler, Leonard; Wigginton, Jon; Withrow, Stephen; Schoenfeldt, Mason; Anderson, Barry.

In: Clinical Cancer Research, Vol. 9, No. 15, 15.11.2003, p. 5442-5453.

Research output: Contribution to journalArticle

Gorlick, R, Anderson, P, Andrulis, I, Arndt, C, Beardsley, GP, Bernstein, M, Bridge, J, Cheung, NK, Dome, JS, Ebb, D, Gardner, T, Gebhardt, M, Grier, H, Hansen, M, Healey, J, Helman, L, Hock, J, Houghton, J, Houghton, P, Huvos, A, Khanna, C, Kieran, M, Kleinerman, E, Ladanyi, M, Lau, C, Malkin, D, Marina, N, Meltzer, P, Meyers, P, Schofield, D, Schwartz, C, Smith, MA, Toretsky, J, Tsokos, M, Wexler, L, Wigginton, J, Withrow, S, Schoenfeldt, M & Anderson, B 2003, 'Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary', Clinical Cancer Research, vol. 9, no. 15, pp. 5442-5453.
Gorlick R, Anderson P, Andrulis I, Arndt C, Beardsley GP, Bernstein M et al. Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary. Clinical Cancer Research. 2003 Nov 15;9(15):5442-5453.
Gorlick, Richard ; Anderson, Peter ; Andrulis, Irene ; Arndt, Carola ; Beardsley, G. Peter ; Bernstein, Mark ; Bridge, Julia ; Cheung, Nai Kong ; Dome, Jeffrey S. ; Ebb, David ; Gardner, Thomas ; Gebhardt, Mark ; Grier, Holcombe ; Hansen, Marc ; Healey, John ; Helman, Lee ; Hock, Janet ; Houghton, Janet ; Houghton, Peter ; Huvos, Andrew ; Khanna, Chand ; Kieran, Mark ; Kleinerman, Eugenie ; Ladanyi, Marc ; Lau, Ching ; Malkin, David ; Marina, Neyssa ; Meltzer, Paul ; Meyers, Paul ; Schofield, Deborah ; Schwartz, Cindy ; Smith, Malcolm A. ; Toretsky, Jeffrey ; Tsokos, Maria ; Wexler, Leonard ; Wigginton, Jon ; Withrow, Stephen ; Schoenfeldt, Mason ; Anderson, Barry. / Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development : Meeting Summary. In: Clinical Cancer Research. 2003 ; Vol. 9, No. 15. pp. 5442-5453.
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