Biomarkers for Early Complications After Hematopoietic Stem Cell Transplantation

Courtney M. Rowan, Sophie Paczesny

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Advances in the field of omics have led to a significant expansion in biomarkers identified for complications after hematopoietic stem cell transplantation (HSCT). Biomarkers can offer an effective method for early identification of a specific disease and can be used to guide therapies. Ongoing investigations to discover biomarkers for acute graft-versus-host disease as well as other post-HSCT complications may improve early diagnosis, prognosis, and the development of new therapeutic targets. The authors review the most recent and validated diagnostic, prognostic, predictive, and response to treatment biomarkers for early complications following HSCT consistent with 2014 NIH consensus on biomarker criteria.

Original languageEnglish (US)
Pages (from-to)61-72
Number of pages12
JournalClinics in Laboratory Medicine
Volume39
Issue number1
DOIs
StatePublished - Mar 2019

Keywords

  • Biomarkers
  • Graft versus host disease
  • Hematopoietic stem cell transplantation
  • Proteomics

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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