Biomedical and behavioral research in nursing homes: Guidelines for ethical investigations

G. A. Sachs, J. Rhymes, C. K. Cassel

Research output: Contribution to journalReview article

27 Scopus citations


As nursing homes become increasingly important sites for biomedical and behavioral research, researchers must address the ethical problems of increased vulnerability and the high prevalence of mental and physical disorders in the nursing home population. Obtaining valid informed consent is but one of the many difficult issues that confronts the investigator in the nursing home. Efforts should be made to involve nursing home residents, as well as family and staff members, in the review of research. The benefits and burdens of research protocols should be equitably distributed, and potential conflicts of interest for staff members and physicians should be minimized or their potential adverse impact ameliorated. Appropriate attention to these ethical concerns may facilitate nursing home research while still safeguarding vulnerable residents. We offer proposed guidelines for the ethical conduct of research in nursing homes in an effort to stimulate discussion among investigators, nursing home staff and residents, residents' families, and ethicists.

Original languageEnglish (US)
Pages (from-to)771-777
Number of pages7
JournalJournal of the American Geriatrics Society
Issue number7
StatePublished - Jan 1 1993
Externally publishedYes

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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