Purpose of review: Most guidelines recommend that seated clinic blood pressure (BP) be targeted to less than 130/80 mmHg in patients with chronic kidney disease (CKD). The evidence underlying these recommendations is the subject of this review. Recent findings: The best evidence to target a certain level of BP in patients with CKD comes from randomized trials. Only three trials have prospectively examined the level to which BP should be lowered. These trials conducted exclusively among patients with CKD have demonstrated that compared to a less aggressive BP goal, a BP goal of less than 130/80 mmHg neither saves lives nor protects the kidney or the cardiovascular system. Summary: It is reasonable to achieve a goal of less than 140/90 mmHg in most patients with CKD. More aggressive lowering is not firmly supported by current data. Since BP control is important, hypertension therapy should be individualized. Individualization through home BP measurements to diagnose, monitor and treat hypertension appears to be an attractive option.
- ambulatory blood pressure
- chronic kidney disease
- home blood pressure monitoring
ASJC Scopus subject areas
- Internal Medicine
Research output: Contribution to journal › Article
TY - JOUR
T1 - Blood pressure goal in chronic kidney disease
T2 - What is the evidence?
AU - Agarwal, Rajiv
PY - 2011/5
Y1 - 2011/5
N2 - Lippincott Williams & Wilkins.
AB - Lippincott Williams & Wilkins.
KW - ambulatory blood pressure
KW - chronic kidney disease
KW - home blood pressure monitoring
KW - hypertension
KW - treatment
UR - http://www.scopus.com/inward/record.url?scp=79955018147&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79955018147&partnerID=8YFLogxK
U2 - 10.1097/MNH.0b013e3283454332
DO - 10.1097/MNH.0b013e3283454332
M3 - Article
VL - 20
SP - 229
EP - 232
JO - Current Opinion in Nephrology and Hypertension
JF - Current Opinion in Nephrology and Hypertension
SN - 1062-4821
IS - 3