Blood pressure goal in chronic kidney disease: What is the evidence?

Research output: Contribution to journalReview article

9 Scopus citations


Purpose of review: Most guidelines recommend that seated clinic blood pressure (BP) be targeted to less than 130/80 mmHg in patients with chronic kidney disease (CKD). The evidence underlying these recommendations is the subject of this review. Recent findings: The best evidence to target a certain level of BP in patients with CKD comes from randomized trials. Only three trials have prospectively examined the level to which BP should be lowered. These trials conducted exclusively among patients with CKD have demonstrated that compared to a less aggressive BP goal, a BP goal of less than 130/80 mmHg neither saves lives nor protects the kidney or the cardiovascular system. Summary: It is reasonable to achieve a goal of less than 140/90 mmHg in most patients with CKD. More aggressive lowering is not firmly supported by current data. Since BP control is important, hypertension therapy should be individualized. Individualization through home BP measurements to diagnose, monitor and treat hypertension appears to be an attractive option.

Original languageEnglish (US)
Pages (from-to)229-232
Number of pages4
JournalCurrent Opinion in Nephrology and Hypertension
Issue number3
StatePublished - May 1 2011


  • ambulatory blood pressure
  • chronic kidney disease
  • home blood pressure monitoring
  • hypertension
  • treatment

ASJC Scopus subject areas

  • Nephrology
  • Internal Medicine

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