Bony demineralization following urinary intestinal diversion

W. S. McDougal, M. O. Koch, C. Shands, R. R. Price

Research output: Contribution to journalArticle

54 Scopus citations

Abstract

The effect of urinary intestinal diversion on bone mineral metabolism was investigated in 78 rats. The animals were divided into sham-operated controls and diverted animals. The diverted animals were given either no supplement, sodium bicarbonate or ascorbic acid for an eight month period. Dual photon densitometry and bone mineral content were determined. Urinary intestinal diversion resulted in a minimal systemic acidosis and little alteration in baseline renal function but a significant decrease in bone calcium content. Oral bicarbonate and ascorbic acid administration prevented the demineralization.

Original languageEnglish (US)
Pages (from-to)853-855
Number of pages3
JournalJournal of Urology
Volume140
Issue number4
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

ASJC Scopus subject areas

  • Urology

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