Borna disease virus antibodies and the deficit syndrome of schizophrenia

Royce W. Waltrip, Robert W. Buchanan, William T. Carpenter, Brian Kirkpatrick, Ann Summerfelt, Alan Breier, Steven A. Rubin, Kathryn M. Carbone

Research output: Contribution to journalArticle

70 Scopus citations

Abstract

We detected anti-Borna disease virus (BDV) antibodies at a 14.4% rate in patients with schizophrenia. The hypothesis of a higher rate of BDV seropositivity in deficit syndrome was borne out in a subset of 64 patients categorized according to the Schedule for the Deficit Syndrome with 5/15 seropositive deficit and 4/49 seropositive nondeficit (p<0.05). This suggests that the antibodies and possibly a BDV-like virus are pathogenetically linked to this form of schizophrenia.

Original languageEnglish (US)
Pages (from-to)253-257
Number of pages5
JournalSchizophrenia Research
Volume23
Issue number3
DOIs
StatePublished - Feb 28 1997
Externally publishedYes

Keywords

  • Borna disease virus
  • deficit syndrome
  • schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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    Waltrip, R. W., Buchanan, R. W., Carpenter, W. T., Kirkpatrick, B., Summerfelt, A., Breier, A., Rubin, S. A., & Carbone, K. M. (1997). Borna disease virus antibodies and the deficit syndrome of schizophrenia. Schizophrenia Research, 23(3), 253-257. https://doi.org/10.1016/S0920-9964(96)00114-4