Bovine Jugular Vein Conduit: A Mid- to Long-Term Institutional Review

Parth M. Patel, Corinne Tan, Nayan Srivastava, Jeremy L. Herrmann, Mark Rodefeld, Mark Turrentine, John Brown

Research output: Contribution to journalArticle

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Abstract

BACKGROUND: Since 1999, we have used the bovine jugular vein conduit for right ventricular outflow tract reconstruction in infants and children. Herein, we review their mid- to long-term outcomes. METHODS: Between 1999 and 2016, 315 bovine jugular vein conduits were implanted in 276 patients. Patients were grouped by age at bovine jugular vein conduit implant: group 1: 0 to 1 years (N = 65), group 2: one to ten years (N = 132), and group 3: older than ten years (N = 118). For survival and hemodynamic analysis, additional group stratification was done based on conduit size. Group small: 12 and 14 mm (N = 75), group medium: 16 and 18 mm (N = 84), and group large: 20 and 22 mm (N = 156). RESULTS: Mean follow-up for groups 1, 2, and 3 was 4.0, 4.9, and 5.9 years, respectively. Early mortality was 9%, 0%, and 1% for groups 1, 2, and 3, respectively ( P < .001). Late mortality was 5%, 2%, and 2% for groups 1, 2, and 3, respectively ( P = .337). Group 1 had the lowest ten-year freedom from conduit failure at 13%, versus 53% and 69% for groups 2 and 3, respectively ( P < .001). A total of 21 (6.6%) patients developed endocarditis, 11 (3.5%) patients required reoperation, and 10 (3.2%) patients required antibiotic therapy alone. CONCLUSIONS: The bovine jugular vein conduit is a useful option for right ventricular outflow tract reconstruction given its easy implantability and acceptable midterm durability.

Original languageEnglish (US)
Pages (from-to)489-495
Number of pages7
JournalWorld journal for pediatric & congenital heart surgery
Volume9
Issue number5
DOIs
StatePublished - Sep 1 2018

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Jugular Veins
Mortality
Survival Analysis
Endocarditis
Reoperation
Hemodynamics
Anti-Bacterial Agents

Keywords

  • CHD—valve lesions
  • heart valve—bioprosthesis
  • pulmonary valve
  • xenograft

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bovine Jugular Vein Conduit : A Mid- to Long-Term Institutional Review. / Patel, Parth M.; Tan, Corinne; Srivastava, Nayan; Herrmann, Jeremy L.; Rodefeld, Mark; Turrentine, Mark; Brown, John.

In: World journal for pediatric & congenital heart surgery, Vol. 9, No. 5, 01.09.2018, p. 489-495.

Research output: Contribution to journalArticle

Patel, Parth M. ; Tan, Corinne ; Srivastava, Nayan ; Herrmann, Jeremy L. ; Rodefeld, Mark ; Turrentine, Mark ; Brown, John. / Bovine Jugular Vein Conduit : A Mid- to Long-Term Institutional Review. In: World journal for pediatric & congenital heart surgery. 2018 ; Vol. 9, No. 5. pp. 489-495.
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