Brain imaging studies in mood and anxiety disorders

Special emphasis on the amygdala

Amit Anand, Anantha Shekhar

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

Human studies attempting to elucidate brain functioning in health and disease are crucial for our understanding of neuropsychiatric disorders. In the past, scientists relied heavily on neurological lesion studies to understand the functional roles of brain areas. In the last few decades, brain imaging research has made it possible to investigate the molecular and synaptic neuronal events as well as the functioning of neuronal networks in vivo, in patients with neuropsychiatric illnesses. In this context, the functional role of the amygdala has been a focus of neuroimaging studies by leading researchers. Several of these researchers presented papers at a conference, entitled The Amygdala in Brain Function: Basic and Clinical Approaches, that provided the basis for this volume. These papers follow this review in the current volume. The present paper briefly summarizes the highlights of the different presentations, focusing on the functional diversity of the amygdala and its role in different neuropsychiatric disorders; reviews the various brain imaging technologies currently available; and discusses the major findings on the pathophysiology and treatment of depression, bipolar disorder, and anxiety disorders.

Original languageEnglish
Pages (from-to)370-388
Number of pages19
JournalAnnals of the New York Academy of Sciences
Volume985
StatePublished - 2003

Fingerprint

Amygdala
Anxiety Disorders
Mood Disorders
Neuroimaging
Brain
Imaging techniques
Research Personnel
Bipolar Disorder
Depression
Technology
Health
Research
Brain Imaging
Therapeutics

Keywords

  • Anxiety
  • Brain imaging
  • Depressionobipolar disorder
  • FMRI
  • Mood
  • MRI
  • MRS
  • OCD
  • Panic disorder
  • PET
  • Phobia
  • PTSD

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Brain imaging studies in mood and anxiety disorders : Special emphasis on the amygdala. / Anand, Amit; Shekhar, Anantha.

In: Annals of the New York Academy of Sciences, Vol. 985, 2003, p. 370-388.

Research output: Contribution to journalArticle

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