Brain Scans, Dexamethasone Therapy, and Brain Tumors

James W. Fletcher, Erica A. George, Robert E. Henry, Robert M. Donati

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Eight men with primary or metastatic brain tumors were examined with brain scans before and after the administration of dexamethasone. All patients demonstrated some improvement in their clinical neurologic status during therapy, and two patients had a dramatic response. Seven of the eight patients examined showed a decrease in the apparent size of the original lesion on repeat brain scan while receiving dexamethasone. Comparison of immediate scans obtained 15 to 20 minutes following the administration of sodium pertechnetate Tc 99m with those obtained two to three hours later suggests that the change in apparent size of the original lesion results from decrease in peritumor edema.

Original languageEnglish (US)
Pages (from-to)1261-1263
Number of pages3
JournalJAMA: The Journal of the American Medical Association
Issue number12
StatePublished - Jun 23 1975
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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