Breathing easier: Addressing the challenges of aerosolizing medications to infants and preschoolers

Jennifer L. Goralski, Stephanie Davis

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

An increasing number of patients are dependent on aerosolized therapy to manage pulmonary diseases, including asthma, cystic fibrosis, and pulmonary arterial hypertension. An aerosol therapy is only useful if it can be appropriately and consistently delivered in the desired dose to the lower respiratory tract. Many factors affect this deposition in young children, including anatomical and physiologic differences between adults and children, patient-mask interface issues, the challenge of administering medication to uncooperative children, and behavioral adherence. Moreover, the techniques used to assess aerosol delivery to pediatric patients need to be carefully evaluated as new therapies and drug-device combinations are tested. In this review, we will address some of the challenges of delivering aerosolized medications to pediatric patients.

Original languageEnglish
Pages (from-to)1069-1073
Number of pages5
JournalRespiratory Medicine
Volume108
Issue number8
DOIs
StatePublished - 2014

Fingerprint

Respiration
Aerosols
Pediatrics
Masks
Combination Drug Therapy
Pulmonary Hypertension
Cystic Fibrosis
Respiratory System
Lung Diseases
Asthma
Equipment and Supplies
Therapeutics

Keywords

  • Adherence
  • Infants
  • MDI
  • Medication
  • Nebulizer
  • Preschoolers

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Medicine(all)

Cite this

Breathing easier : Addressing the challenges of aerosolizing medications to infants and preschoolers. / Goralski, Jennifer L.; Davis, Stephanie.

In: Respiratory Medicine, Vol. 108, No. 8, 2014, p. 1069-1073.

Research output: Contribution to journalArticle

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