Breathing easier: Addressing the challenges of aerosolizing medications to infants and preschoolers

Jennifer L. Goralski, Stephanie D. Davis

Research output: Contribution to journalReview article

11 Scopus citations

Abstract

An increasing number of patients are dependent on aerosolized therapy to manage pulmonary diseases, including asthma, cystic fibrosis, and pulmonary arterial hypertension. An aerosol therapy is only useful if it can be appropriately and consistently delivered in the desired dose to the lower respiratory tract. Many factors affect this deposition in young children, including anatomical and physiologic differences between adults and children, patient-mask interface issues, the challenge of administering medication to uncooperative children, and behavioral adherence. Moreover, the techniques used to assess aerosol delivery to pediatric patients need to be carefully evaluated as new therapies and drug-device combinations are tested. In this review, we will address some of the challenges of delivering aerosolized medications to pediatric patients.

Original languageEnglish (US)
Pages (from-to)1069-1074
Number of pages6
JournalRespiratory Medicine
Volume108
Issue number8
DOIs
StatePublished - Aug 2014

Keywords

  • Adherence
  • Infants
  • MDI
  • Medication
  • Nebulizer
  • Preschoolers

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Medicine(all)

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