Brief report: Pediatric cancer burden and treatment resources within the pediatric IeDEA consortium

Steven A. Brown, Salma Abbas, Mary Ann Davies, Torsak Bunupuradah, Annette H. Sohn, Karl Günter Technau, Lorna Renner, Valériane Leroy, Andrew Edmonds, Marcel Yotebieng, Catherine C. McGowan, Stephany N. Duda, Lynne Mofenson, Beverly Musick, Kara Wools-Kaloustian

Research output: Contribution to journalArticle

Abstract

Introduction: The incidence and treatment of cancer in HIV-infected children from resource-limited settings has not been extensively studied. Objectives: Develop and implement a cross-sectional survey to evaluate pediatric cancer burden, diagnostic modalities in use, and treatment availability as perceived by HIV clinic staff at regional International Epidemiology Databases to Evaluate AIDS (IeDEA) sites. Methods: IeDEA regional investigators developed a cross-sectional clinical site survey which included questions on the numbers and types of pediatric cancers observed, modalities used to treat identified cancers, and treatment options available at individual sites in the Asia-Pacific, Latin America, Central Africa, East Africa, West Africa, and Southern Africa regions. Results: Kaposi sarcoma, non-Hodgkin lymphoma, and Burkitt lymphoma were reported by site personnel to be the most prevalent types of cancer in the pediatric HIV population. Survey results indicate that access to comprehensive cancer treatment modalities is very limited for children in these regions despite HIV care and treatment sites reporting that they diagnose pediatric cancers. Responses also showed that evaluating cancer in the pediatric HIV population is a challenge due to a lack of resources and varying treatment availability within regions. Conclusions: Further study is needed to increase our understanding of the changing epidemiology of cancer in HIV-infected pediatric populations. Increased financial and technical resources are critical to aid in the advancement of health services to support treatment of these children in resource-constrained settings.

Original languageEnglish (US)
Pages (from-to)60-64
Number of pages5
JournalJournal of Acquired Immune Deficiency Syndromes
Volume76
Issue number1
DOIs
StatePublished - Sep 1 2017

Fingerprint

Acquired Immunodeficiency Syndrome
Epidemiology
Databases
Pediatrics
HIV
Neoplasms
Therapeutics
Population
Central Africa
Southern Africa
Eastern Africa
Western Africa
Burkitt Lymphoma
Latin America
Kaposi's Sarcoma
Non-Hodgkin's Lymphoma
Health Services
Cross-Sectional Studies
Research Personnel
Incidence

Keywords

  • cancer
  • HIV
  • pediatrics
  • resource-limited settings

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Brief report : Pediatric cancer burden and treatment resources within the pediatric IeDEA consortium. / Brown, Steven A.; Abbas, Salma; Davies, Mary Ann; Bunupuradah, Torsak; Sohn, Annette H.; Technau, Karl Günter; Renner, Lorna; Leroy, Valériane; Edmonds, Andrew; Yotebieng, Marcel; McGowan, Catherine C.; Duda, Stephany N.; Mofenson, Lynne; Musick, Beverly; Wools-Kaloustian, Kara.

In: Journal of Acquired Immune Deficiency Syndromes, Vol. 76, No. 1, 01.09.2017, p. 60-64.

Research output: Contribution to journalArticle

Brown, SA, Abbas, S, Davies, MA, Bunupuradah, T, Sohn, AH, Technau, KG, Renner, L, Leroy, V, Edmonds, A, Yotebieng, M, McGowan, CC, Duda, SN, Mofenson, L, Musick, B & Wools-Kaloustian, K 2017, 'Brief report: Pediatric cancer burden and treatment resources within the pediatric IeDEA consortium', Journal of Acquired Immune Deficiency Syndromes, vol. 76, no. 1, pp. 60-64. https://doi.org/10.1097/QAI.0000000000001453
Brown, Steven A. ; Abbas, Salma ; Davies, Mary Ann ; Bunupuradah, Torsak ; Sohn, Annette H. ; Technau, Karl Günter ; Renner, Lorna ; Leroy, Valériane ; Edmonds, Andrew ; Yotebieng, Marcel ; McGowan, Catherine C. ; Duda, Stephany N. ; Mofenson, Lynne ; Musick, Beverly ; Wools-Kaloustian, Kara. / Brief report : Pediatric cancer burden and treatment resources within the pediatric IeDEA consortium. In: Journal of Acquired Immune Deficiency Syndromes. 2017 ; Vol. 76, No. 1. pp. 60-64.
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