Bronchoscopy in the diagnosis of respiratory infections

David C. Mares, David S. Wilkes

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In recent years, several factors have altered the spectrum of respiratory infections and their likelihood of response to empiric treatment. Altered microbial resistance has led to the possible need for specific etiologic diagnosis in some hospital-acquired infections in the normal host. In the immune-compromised host, the spectrum of atypical presentations and unusual organisms limits the clinician's ability to choose effective empiric therapies. In the normal host, bronchoscopic diagnosis seems to be most useful in the groups with severe community-acquired pneumonia or poor response to therapy for community-acquired pneumonia. The group of patients with ventilator-associated pneumonia has been well-researched and the bronchoscopic techniques tend to show increased sensitivity over other diagnostic means, but this has not been proven to alter morbidity, mortality, or cost effectiveness. The immune-compromised host is commonly infected by organisms not easily diagnosed by other means and is thus unable to be treated empirically. Bronchoscopic diagnostic techniques play a larger and more clearly delineated role in these populations, including the patient populations with solid organ transplants, bone marrow transplants, and AIDS.

Original languageEnglish
Pages (from-to)123-129
Number of pages7
JournalCurrent Opinion in Pulmonary Medicine
Volume4
Issue number3
StatePublished - 1998

Fingerprint

Bronchoscopy
Respiratory Tract Infections
Pneumonia
Transplants
Ventilator-Associated Pneumonia
Cross Infection
Population
Cost-Benefit Analysis
Acquired Immunodeficiency Syndrome
Therapeutics
Bone Marrow
Morbidity
Mortality

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Bronchoscopy in the diagnosis of respiratory infections. / Mares, David C.; Wilkes, David S.

In: Current Opinion in Pulmonary Medicine, Vol. 4, No. 3, 1998, p. 123-129.

Research output: Contribution to journalArticle

Mares, DC & Wilkes, DS 1998, 'Bronchoscopy in the diagnosis of respiratory infections', Current Opinion in Pulmonary Medicine, vol. 4, no. 3, pp. 123-129.
Mares, David C. ; Wilkes, David S. / Bronchoscopy in the diagnosis of respiratory infections. In: Current Opinion in Pulmonary Medicine. 1998 ; Vol. 4, No. 3. pp. 123-129.
@article{a1354f22430043a6b7f0badbeef43140,
title = "Bronchoscopy in the diagnosis of respiratory infections",
abstract = "In recent years, several factors have altered the spectrum of respiratory infections and their likelihood of response to empiric treatment. Altered microbial resistance has led to the possible need for specific etiologic diagnosis in some hospital-acquired infections in the normal host. In the immune-compromised host, the spectrum of atypical presentations and unusual organisms limits the clinician's ability to choose effective empiric therapies. In the normal host, bronchoscopic diagnosis seems to be most useful in the groups with severe community-acquired pneumonia or poor response to therapy for community-acquired pneumonia. The group of patients with ventilator-associated pneumonia has been well-researched and the bronchoscopic techniques tend to show increased sensitivity over other diagnostic means, but this has not been proven to alter morbidity, mortality, or cost effectiveness. The immune-compromised host is commonly infected by organisms not easily diagnosed by other means and is thus unable to be treated empirically. Bronchoscopic diagnostic techniques play a larger and more clearly delineated role in these populations, including the patient populations with solid organ transplants, bone marrow transplants, and AIDS.",
author = "Mares, {David C.} and Wilkes, {David S.}",
year = "1998",
language = "English",
volume = "4",
pages = "123--129",
journal = "Current Opinion in Pulmonary Medicine",
issn = "1070-5287",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Bronchoscopy in the diagnosis of respiratory infections

AU - Mares, David C.

AU - Wilkes, David S.

PY - 1998

Y1 - 1998

N2 - In recent years, several factors have altered the spectrum of respiratory infections and their likelihood of response to empiric treatment. Altered microbial resistance has led to the possible need for specific etiologic diagnosis in some hospital-acquired infections in the normal host. In the immune-compromised host, the spectrum of atypical presentations and unusual organisms limits the clinician's ability to choose effective empiric therapies. In the normal host, bronchoscopic diagnosis seems to be most useful in the groups with severe community-acquired pneumonia or poor response to therapy for community-acquired pneumonia. The group of patients with ventilator-associated pneumonia has been well-researched and the bronchoscopic techniques tend to show increased sensitivity over other diagnostic means, but this has not been proven to alter morbidity, mortality, or cost effectiveness. The immune-compromised host is commonly infected by organisms not easily diagnosed by other means and is thus unable to be treated empirically. Bronchoscopic diagnostic techniques play a larger and more clearly delineated role in these populations, including the patient populations with solid organ transplants, bone marrow transplants, and AIDS.

AB - In recent years, several factors have altered the spectrum of respiratory infections and their likelihood of response to empiric treatment. Altered microbial resistance has led to the possible need for specific etiologic diagnosis in some hospital-acquired infections in the normal host. In the immune-compromised host, the spectrum of atypical presentations and unusual organisms limits the clinician's ability to choose effective empiric therapies. In the normal host, bronchoscopic diagnosis seems to be most useful in the groups with severe community-acquired pneumonia or poor response to therapy for community-acquired pneumonia. The group of patients with ventilator-associated pneumonia has been well-researched and the bronchoscopic techniques tend to show increased sensitivity over other diagnostic means, but this has not been proven to alter morbidity, mortality, or cost effectiveness. The immune-compromised host is commonly infected by organisms not easily diagnosed by other means and is thus unable to be treated empirically. Bronchoscopic diagnostic techniques play a larger and more clearly delineated role in these populations, including the patient populations with solid organ transplants, bone marrow transplants, and AIDS.

UR - http://www.scopus.com/inward/record.url?scp=0032062157&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032062157&partnerID=8YFLogxK

M3 - Article

C2 - 9675513

AN - SCOPUS:0032062157

VL - 4

SP - 123

EP - 129

JO - Current Opinion in Pulmonary Medicine

JF - Current Opinion in Pulmonary Medicine

SN - 1070-5287

IS - 3

ER -