Building a surface atlas of hippocampal subfields from high resolution T2-weighted MRI scans using landmark-free surface registration

Shan Cong, Maher Rizkalla, Paul Salama, Shannon L. Risacher, John D. West, Yu Chien Wu, Liana Apostolova, Eileen Tallman, Andrew J. Saykin, Li Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The hippocampus is widely studied in neuroimaging field as it plays important roles in memory and learning. However, the critical subfield information is often not explored in most hippocampal studies. We previously proposed a method for hippocampal subfield morphometry by integrating FreeSurfer, FSL, and SPHARM tools. But this method had some limitations, including the analysis of T1-weighted MRI scans without detailed subfield information and hippocampal registration without using important subfield information. To bridge these gaps, in this work, we propose a new framework for building a surface atlas of hippocampal subfields from high resolution T2-weighted MRI scans by integrating state-of-The-Art methods for automated segmentation of hippocampal subfields and landmark-free, subfieldaware registration of hippocampal surfaces. Our experimental results have shown the promise of the new framework.

Original languageEnglish (US)
Title of host publication2016 IEEE 59th International Midwest Symposium on Circuits and Systems, MWSCAS 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781509009169
DOIs
StatePublished - Jul 2 2016
Event59th IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2016 - Abu Dhabi, United Arab Emirates
Duration: Oct 16 2016Oct 19 2016

Publication series

NameMidwest Symposium on Circuits and Systems
Volume0
ISSN (Print)1548-3746

Other

Other59th IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2016
CountryUnited Arab Emirates
CityAbu Dhabi
Period10/16/1610/19/16

    Fingerprint

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

Cite this

Cong, S., Rizkalla, M., Salama, P., Risacher, S. L., West, J. D., Wu, Y. C., Apostolova, L., Tallman, E., Saykin, A. J., & Shen, L. (2016). Building a surface atlas of hippocampal subfields from high resolution T2-weighted MRI scans using landmark-free surface registration. In 2016 IEEE 59th International Midwest Symposium on Circuits and Systems, MWSCAS 2016 [7870109] (Midwest Symposium on Circuits and Systems; Vol. 0). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MWSCAS.2016.7870109