Can colonic manometry studies be done on the day of colonic motility catheter placement?

Rana F. Ammoury, John D. Emhardt, William B. Aitchison, Debra S. Horn, Joseph Croffie

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background and Aims: Colonic manometry has been used to assess colonic neuromuscular integrity in pediatric patients with severe constipation unresponsive to standard medical therapy and to tailor their treatment plans. There are presently no available standard protocols for conducting colonic manometry studies. The aim of the present study was to determine whether colonic manometry studies can be conducted on the same day the colonic motility catheters are placed and to compare the effects of inhaled sevoflurane versus intravenous propofol, used during catheter placement, on colonic motility. Methods: Twenty patients, randomized to receive sevoflurane or propofol during catheter placement, underwent colonic manometry on the day of catheter placement as well as the day after. The total motility index (MI), change in MI in response to a meal and bisacodyl, and presence of high-amplitude propagating contractions were compared between the 2 studies for each patient. Results: Ten patients were allocated to sevoflurane and 10 patients to propofol. A total of 8 (80%) patients in the sevoflurane group and 9 (90%) patients in the propofol group had no differences in their studies between days 1 and 2 when the tracings were interpreted manually for gross evidence of high-amplitude propagating contractions and gastrocolonic reflex. Similarly, there was no change in the total MI between studies done on days 1 and 2 in either sevoflurane (978±232 vs 978±184; P=0.99) or propofol (968±200 vs 1078±227; P=0.29) group. When comparing change in MI in response to a meal or bisacodyl between the 2 days, there was no statistical difference noted in either group. Conclusions: Colonic manometry studies can be conducted as early as 4hours following catheter placement with either propofol or sevoflurane used for anesthesia.

Original languageEnglish
Pages (from-to)278-282
Number of pages5
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume55
Issue number3
DOIs
StatePublished - Sep 2012

Fingerprint

Manometry
Propofol
Catheters
Bisacodyl
Meals
Constipation
Reflex
sevoflurane
Anesthesia
Pediatrics
Therapeutics

Keywords

  • colonic manometry
  • colonic motility
  • inhaled anesthetic
  • intravenous anesthetic
  • propofol
  • sevoflurane

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health

Cite this

Can colonic manometry studies be done on the day of colonic motility catheter placement? / Ammoury, Rana F.; Emhardt, John D.; Aitchison, William B.; Horn, Debra S.; Croffie, Joseph.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 55, No. 3, 09.2012, p. 278-282.

Research output: Contribution to journalArticle

Ammoury, Rana F. ; Emhardt, John D. ; Aitchison, William B. ; Horn, Debra S. ; Croffie, Joseph. / Can colonic manometry studies be done on the day of colonic motility catheter placement?. In: Journal of Pediatric Gastroenterology and Nutrition. 2012 ; Vol. 55, No. 3. pp. 278-282.
@article{0d95ea9886134ed69a7068a403a5ab2a,
title = "Can colonic manometry studies be done on the day of colonic motility catheter placement?",
abstract = "Background and Aims: Colonic manometry has been used to assess colonic neuromuscular integrity in pediatric patients with severe constipation unresponsive to standard medical therapy and to tailor their treatment plans. There are presently no available standard protocols for conducting colonic manometry studies. The aim of the present study was to determine whether colonic manometry studies can be conducted on the same day the colonic motility catheters are placed and to compare the effects of inhaled sevoflurane versus intravenous propofol, used during catheter placement, on colonic motility. Methods: Twenty patients, randomized to receive sevoflurane or propofol during catheter placement, underwent colonic manometry on the day of catheter placement as well as the day after. The total motility index (MI), change in MI in response to a meal and bisacodyl, and presence of high-amplitude propagating contractions were compared between the 2 studies for each patient. Results: Ten patients were allocated to sevoflurane and 10 patients to propofol. A total of 8 (80{\%}) patients in the sevoflurane group and 9 (90{\%}) patients in the propofol group had no differences in their studies between days 1 and 2 when the tracings were interpreted manually for gross evidence of high-amplitude propagating contractions and gastrocolonic reflex. Similarly, there was no change in the total MI between studies done on days 1 and 2 in either sevoflurane (978±232 vs 978±184; P=0.99) or propofol (968±200 vs 1078±227; P=0.29) group. When comparing change in MI in response to a meal or bisacodyl between the 2 days, there was no statistical difference noted in either group. Conclusions: Colonic manometry studies can be conducted as early as 4hours following catheter placement with either propofol or sevoflurane used for anesthesia.",
keywords = "colonic manometry, colonic motility, inhaled anesthetic, intravenous anesthetic, propofol, sevoflurane",
author = "Ammoury, {Rana F.} and Emhardt, {John D.} and Aitchison, {William B.} and Horn, {Debra S.} and Joseph Croffie",
year = "2012",
month = "9",
doi = "10.1097/MPG.0b013e31824ac64c",
language = "English",
volume = "55",
pages = "278--282",
journal = "Journal of Pediatric Gastroenterology and Nutrition",
issn = "0277-2116",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Can colonic manometry studies be done on the day of colonic motility catheter placement?

AU - Ammoury, Rana F.

AU - Emhardt, John D.

AU - Aitchison, William B.

AU - Horn, Debra S.

AU - Croffie, Joseph

PY - 2012/9

Y1 - 2012/9

N2 - Background and Aims: Colonic manometry has been used to assess colonic neuromuscular integrity in pediatric patients with severe constipation unresponsive to standard medical therapy and to tailor their treatment plans. There are presently no available standard protocols for conducting colonic manometry studies. The aim of the present study was to determine whether colonic manometry studies can be conducted on the same day the colonic motility catheters are placed and to compare the effects of inhaled sevoflurane versus intravenous propofol, used during catheter placement, on colonic motility. Methods: Twenty patients, randomized to receive sevoflurane or propofol during catheter placement, underwent colonic manometry on the day of catheter placement as well as the day after. The total motility index (MI), change in MI in response to a meal and bisacodyl, and presence of high-amplitude propagating contractions were compared between the 2 studies for each patient. Results: Ten patients were allocated to sevoflurane and 10 patients to propofol. A total of 8 (80%) patients in the sevoflurane group and 9 (90%) patients in the propofol group had no differences in their studies between days 1 and 2 when the tracings were interpreted manually for gross evidence of high-amplitude propagating contractions and gastrocolonic reflex. Similarly, there was no change in the total MI between studies done on days 1 and 2 in either sevoflurane (978±232 vs 978±184; P=0.99) or propofol (968±200 vs 1078±227; P=0.29) group. When comparing change in MI in response to a meal or bisacodyl between the 2 days, there was no statistical difference noted in either group. Conclusions: Colonic manometry studies can be conducted as early as 4hours following catheter placement with either propofol or sevoflurane used for anesthesia.

AB - Background and Aims: Colonic manometry has been used to assess colonic neuromuscular integrity in pediatric patients with severe constipation unresponsive to standard medical therapy and to tailor their treatment plans. There are presently no available standard protocols for conducting colonic manometry studies. The aim of the present study was to determine whether colonic manometry studies can be conducted on the same day the colonic motility catheters are placed and to compare the effects of inhaled sevoflurane versus intravenous propofol, used during catheter placement, on colonic motility. Methods: Twenty patients, randomized to receive sevoflurane or propofol during catheter placement, underwent colonic manometry on the day of catheter placement as well as the day after. The total motility index (MI), change in MI in response to a meal and bisacodyl, and presence of high-amplitude propagating contractions were compared between the 2 studies for each patient. Results: Ten patients were allocated to sevoflurane and 10 patients to propofol. A total of 8 (80%) patients in the sevoflurane group and 9 (90%) patients in the propofol group had no differences in their studies between days 1 and 2 when the tracings were interpreted manually for gross evidence of high-amplitude propagating contractions and gastrocolonic reflex. Similarly, there was no change in the total MI between studies done on days 1 and 2 in either sevoflurane (978±232 vs 978±184; P=0.99) or propofol (968±200 vs 1078±227; P=0.29) group. When comparing change in MI in response to a meal or bisacodyl between the 2 days, there was no statistical difference noted in either group. Conclusions: Colonic manometry studies can be conducted as early as 4hours following catheter placement with either propofol or sevoflurane used for anesthesia.

KW - colonic manometry

KW - colonic motility

KW - inhaled anesthetic

KW - intravenous anesthetic

KW - propofol

KW - sevoflurane

UR - http://www.scopus.com/inward/record.url?scp=84865772702&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84865772702&partnerID=8YFLogxK

U2 - 10.1097/MPG.0b013e31824ac64c

DO - 10.1097/MPG.0b013e31824ac64c

M3 - Article

C2 - 22258291

AN - SCOPUS:84865772702

VL - 55

SP - 278

EP - 282

JO - Journal of Pediatric Gastroenterology and Nutrition

JF - Journal of Pediatric Gastroenterology and Nutrition

SN - 0277-2116

IS - 3

ER -