Cancer and comorbidity: Redefining chronic diseases

Karen S. Ogle, G. Marie Swanson, Nancy Woods, Faouzi Azzouz

    Research output: Contribution to journalArticle

    216 Citations (Scopus)

    Abstract

    BACKGROUND. A narrow subspecialty model of cancer care has led to cancer treatment often being given outside the full medical context of the patient. The full range of comorbid illness must be considered in all aspects of diagnosis and treatment. This study was conducted to describe the prevalence of comorbidity in cancer patients and examine its relation with multiple demographic and clinical variables. METHODS. A case comparison study of 15,626 population-based incident cases of cancer was conducted between 1984- 1992 in 3 metropolitan Detroit counties (a National Cancer Institute Surveillance, Epidemiology, and End Results program). Chronic disease status and demographics were collected by self-report; cancer diagnoses and staging were obtained by medical record review. Univariate and multiple logistic regression analyses were performed. RESULTS. Comorbidity was present in 68.7% of cancer patients, and 32.6% of these individuals had ≥2 comorbid conditions. Frequency was increased in the elderly, African-American patients (particularly African-American women), smokers, and those with lower socioeconomic status. Rates also appeared to vary by specific tumor site. CONCLUSIONS. Comorbid chronic diseases are common in persons with cancer. The prevalence of comorbidities has important clinical, health service, and research implications. The disease specific model of oncology may limit appropriate care for these patients, and enhanced integration of primary care into the ongoing management of cancer may offer better outcomes.

    Original languageEnglish (US)
    Pages (from-to)653-663
    Number of pages11
    JournalCancer
    Volume88
    Issue number3
    DOIs
    StatePublished - Feb 1 2000

    Fingerprint

    Comorbidity
    Chronic Disease
    Neoplasms
    African Americans
    Demography
    SEER Program
    National Cancer Institute (U.S.)
    Neoplasm Staging
    Health Services Research
    Social Class
    Self Report
    Medical Records
    Case-Control Studies
    Primary Health Care
    Patient Care
    Logistic Models
    Regression Analysis
    Therapeutics
    Population

    Keywords

    • Cancer
    • Chronic disease
    • Comorbidity
    • Diagnosis
    • Treatment

    ASJC Scopus subject areas

    • Oncology
    • Cancer Research

    Cite this

    Cancer and comorbidity : Redefining chronic diseases. / Ogle, Karen S.; Swanson, G. Marie; Woods, Nancy; Azzouz, Faouzi.

    In: Cancer, Vol. 88, No. 3, 01.02.2000, p. 653-663.

    Research output: Contribution to journalArticle

    Ogle, Karen S. ; Swanson, G. Marie ; Woods, Nancy ; Azzouz, Faouzi. / Cancer and comorbidity : Redefining chronic diseases. In: Cancer. 2000 ; Vol. 88, No. 3. pp. 653-663.
    @article{e99cb6c252914e82b4a7733c52b8350c,
    title = "Cancer and comorbidity: Redefining chronic diseases",
    abstract = "BACKGROUND. A narrow subspecialty model of cancer care has led to cancer treatment often being given outside the full medical context of the patient. The full range of comorbid illness must be considered in all aspects of diagnosis and treatment. This study was conducted to describe the prevalence of comorbidity in cancer patients and examine its relation with multiple demographic and clinical variables. METHODS. A case comparison study of 15,626 population-based incident cases of cancer was conducted between 1984- 1992 in 3 metropolitan Detroit counties (a National Cancer Institute Surveillance, Epidemiology, and End Results program). Chronic disease status and demographics were collected by self-report; cancer diagnoses and staging were obtained by medical record review. Univariate and multiple logistic regression analyses were performed. RESULTS. Comorbidity was present in 68.7{\%} of cancer patients, and 32.6{\%} of these individuals had ≥2 comorbid conditions. Frequency was increased in the elderly, African-American patients (particularly African-American women), smokers, and those with lower socioeconomic status. Rates also appeared to vary by specific tumor site. CONCLUSIONS. Comorbid chronic diseases are common in persons with cancer. The prevalence of comorbidities has important clinical, health service, and research implications. The disease specific model of oncology may limit appropriate care for these patients, and enhanced integration of primary care into the ongoing management of cancer may offer better outcomes.",
    keywords = "Cancer, Chronic disease, Comorbidity, Diagnosis, Treatment",
    author = "Ogle, {Karen S.} and Swanson, {G. Marie} and Nancy Woods and Faouzi Azzouz",
    year = "2000",
    month = "2",
    day = "1",
    doi = "10.1002/(SICI)1097-0142(20000201)88:3<653::AID-CNCR24>3.0.CO;2-1",
    language = "English (US)",
    volume = "88",
    pages = "653--663",
    journal = "Cancer",
    issn = "0008-543X",
    publisher = "John Wiley and Sons Inc.",
    number = "3",

    }

    TY - JOUR

    T1 - Cancer and comorbidity

    T2 - Redefining chronic diseases

    AU - Ogle, Karen S.

    AU - Swanson, G. Marie

    AU - Woods, Nancy

    AU - Azzouz, Faouzi

    PY - 2000/2/1

    Y1 - 2000/2/1

    N2 - BACKGROUND. A narrow subspecialty model of cancer care has led to cancer treatment often being given outside the full medical context of the patient. The full range of comorbid illness must be considered in all aspects of diagnosis and treatment. This study was conducted to describe the prevalence of comorbidity in cancer patients and examine its relation with multiple demographic and clinical variables. METHODS. A case comparison study of 15,626 population-based incident cases of cancer was conducted between 1984- 1992 in 3 metropolitan Detroit counties (a National Cancer Institute Surveillance, Epidemiology, and End Results program). Chronic disease status and demographics were collected by self-report; cancer diagnoses and staging were obtained by medical record review. Univariate and multiple logistic regression analyses were performed. RESULTS. Comorbidity was present in 68.7% of cancer patients, and 32.6% of these individuals had ≥2 comorbid conditions. Frequency was increased in the elderly, African-American patients (particularly African-American women), smokers, and those with lower socioeconomic status. Rates also appeared to vary by specific tumor site. CONCLUSIONS. Comorbid chronic diseases are common in persons with cancer. The prevalence of comorbidities has important clinical, health service, and research implications. The disease specific model of oncology may limit appropriate care for these patients, and enhanced integration of primary care into the ongoing management of cancer may offer better outcomes.

    AB - BACKGROUND. A narrow subspecialty model of cancer care has led to cancer treatment often being given outside the full medical context of the patient. The full range of comorbid illness must be considered in all aspects of diagnosis and treatment. This study was conducted to describe the prevalence of comorbidity in cancer patients and examine its relation with multiple demographic and clinical variables. METHODS. A case comparison study of 15,626 population-based incident cases of cancer was conducted between 1984- 1992 in 3 metropolitan Detroit counties (a National Cancer Institute Surveillance, Epidemiology, and End Results program). Chronic disease status and demographics were collected by self-report; cancer diagnoses and staging were obtained by medical record review. Univariate and multiple logistic regression analyses were performed. RESULTS. Comorbidity was present in 68.7% of cancer patients, and 32.6% of these individuals had ≥2 comorbid conditions. Frequency was increased in the elderly, African-American patients (particularly African-American women), smokers, and those with lower socioeconomic status. Rates also appeared to vary by specific tumor site. CONCLUSIONS. Comorbid chronic diseases are common in persons with cancer. The prevalence of comorbidities has important clinical, health service, and research implications. The disease specific model of oncology may limit appropriate care for these patients, and enhanced integration of primary care into the ongoing management of cancer may offer better outcomes.

    KW - Cancer

    KW - Chronic disease

    KW - Comorbidity

    KW - Diagnosis

    KW - Treatment

    UR - http://www.scopus.com/inward/record.url?scp=0034141485&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0034141485&partnerID=8YFLogxK

    U2 - 10.1002/(SICI)1097-0142(20000201)88:3<653::AID-CNCR24>3.0.CO;2-1

    DO - 10.1002/(SICI)1097-0142(20000201)88:3<653::AID-CNCR24>3.0.CO;2-1

    M3 - Article

    C2 - 10649261

    AN - SCOPUS:0034141485

    VL - 88

    SP - 653

    EP - 663

    JO - Cancer

    JF - Cancer

    SN - 0008-543X

    IS - 3

    ER -