Carinaplasty Airway Closure: A Technique for Right Pneumonectomy

Kenneth Kesler, Zane T. Hammoud, Karen Rieger, Laura E. Kruter, Menggang Yu, John Brown

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Bronchopleural fistula remains a significant source of morbidity and mortality after right pneumonectomy. We reviewed our initial experience with a novel "carinaplasty" airway closure technique aimed at reducing the risks of bronchopleural fistula. Methods: Since 2003, 51 consecutive patients who required right pneumonectomy at our institution underwent carinaplasty airway closure. Malignancy was the indication for pneumonectomy in all but 2 patients. Eighteen patients received preoperative radiation therapy, including 5 patients who received 6000 cGy or more. Postoperatively, 17 patients required mechanical ventilation for an average of 13 days (range, 3 to 42 days). Results: Six operative deaths occurred, four (8.6%) of which were in the 46 patients who did not receive preoperative bleomycin. All deaths were secondary to respiratory failure. None of these patients demonstrated bronchopleural fistula despite mechanical ventilation for up to 30 days. In 2 patients, a small (≤2 mm) bronchopleural fistula developed at 3 and 4 months after operation, respectively. Both patients presented with minor symptoms and spontaneously healed within 1 month after open drainage. Conclusions: These data suggest that the carinaplasty airway closure may reduce the morbidity and mortality of bronchopleural fistula after right pneumonectomy. We speculate mechanisms include elimination of the bronchial stump diverticulum in combination with more submucosal blood supply at the suture line compared with the standard bronchial closures. We currently consider carinaplasty airway closure the technique of choice at our institution and plan continued evaluation.

Original languageEnglish
Pages (from-to)1178-1186
Number of pages9
JournalAnnals of Thoracic Surgery
Volume85
Issue number4
DOIs
StatePublished - Apr 2008

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Pneumonectomy
Fistula
Artificial Respiration
Morbidity
Mortality
Diverticulum
Bleomycin
Respiratory Insufficiency
Sutures
Drainage
Radiotherapy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Carinaplasty Airway Closure : A Technique for Right Pneumonectomy. / Kesler, Kenneth; Hammoud, Zane T.; Rieger, Karen; Kruter, Laura E.; Yu, Menggang; Brown, John.

In: Annals of Thoracic Surgery, Vol. 85, No. 4, 04.2008, p. 1178-1186.

Research output: Contribution to journalArticle

Kesler, Kenneth ; Hammoud, Zane T. ; Rieger, Karen ; Kruter, Laura E. ; Yu, Menggang ; Brown, John. / Carinaplasty Airway Closure : A Technique for Right Pneumonectomy. In: Annals of Thoracic Surgery. 2008 ; Vol. 85, No. 4. pp. 1178-1186.
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